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Nutrición Hospitalaria

On-line version ISSN 1699-5198Print version ISSN 0212-1611

Nutr. Hosp. vol.31 n.6 Madrid Jun. 2015 

ORIGINAL / Obesidad


Association between serum Fe levels and obesity: a meta-analysis

La asociación entre los niveles séricos de hierro y la obesidad: un metaanálisis



Lijuan Yang1, Yi Chen2, Mi Lu3, Lei Liu4 and Liuxia Shi5

1Department of Physiology, Bengbu Medical College, Bengbu, Anhui 233030.
2School of clinic medicine, Wannan Medical College, Wuhu, Anhui 241002.
3School of medical imaging and laboratory, Wannan Medical College, Wuhu, Anhui 241002.
4Department of nephropathy, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004.
5School of Stomatology, Wannan Medical College, Wuhu, Anhui 241001 China.*




The purpose of this study is to clarify the association between serum Fe levels and Obesity using a meta-analysis approach. We searched eligible papers on the relevance published between 2006 and 2014 from the PubMed and the Chinese National Knowledge Infrastructure. Review Manage software was used to collect and analysis the date cited in the papers.6 eligible articles with 934 subjects from 40 case-control studies were identified. Overall,polled analysis indicated that subjects with obesity had lower Fe levels than healthy controls [standardized mean difference (SMD) = -0.738,95%confidence interval (CI) = (-1.228,-0.247)]. Thus, dietary supplement of Fe is recommended to prevent obesity.

Key words: Fe. Serum. Obesity. Meta-analysis.


El objetivo de este estudio es determinar la asociación entre los niveles séricos de hierro y la obesidad mediante un metaanálisis. Hemos buscado los documentos sobre la pertinencia, publicados entre 2006 y 2014 por PubMed y China National Knowledge Infrastructure. El examen se utiliza para recoger y gestionar el software de análisis de la fecha citada en los documentos. Se eligieron seis artículos en los que se identificaron 934 sujetos de entre 40 estudios de casos y controles. En general, los encuestados indicaron que los sujetos con obesidad tenían menores niveles de hierro que los controles sanos [diferencia de promedios estandarizados (DPE) = - 0.738,95% intervalo de confianza (IC) = (-1.228,-0.247)]. Por lo tanto, se recomienda un suplemento dietético de hierro para prevenir la obesidad.

Palabras clave: Hierro. Suero. Obesidad. Metaanálisis.

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