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Nutrición Hospitalaria

On-line version ISSN 1699-5198Print version ISSN 0212-1611

Nutr. Hosp. vol.32 n.4 Madrid Oct. 2015 



Bioactive substances with preventive effect in cardiovascular diseases

Sustancias bioactivas con efecto preventivo en la enfermedad cardiovascular



Juana Mulero1, José Abellán2, Pilar Zafrilla1, Diego Amores1 and Pilar Hernández Sánchez1

1Department of Food Technology and Nutrition. Universidad Católica San Antonio de Murcia.
2Cardiovascular Risk Chair. Universidad Católica San Antonio de Murcia. España.




The effect of diet on cardiovascular disease prevention has been widely studied for many years. Numerous studies have confirmed that diets rich in fruits and vegetables (Mediterranean diet) are beneficial to the cardiovascular system and various bioactive food components have preventive effect on chronic diseases such as cardiovascular disease. In this paper we review the effect of bioactive substances included in the group of flavonoids (catechins and proanthocyanidins, anthocyanins and isoflavones), stilbenes such as resveratrol, bioactive peptides, plant sterols and polyunsaturated fatty acids omega- 3 on the cardiovascular system.

Key words: Cardiovascular disease. Catechins. Anthocyanidins. Anthocyanins. Resveratrol. Omega-3.


El efecto de la dieta sobre la prevención de las enfermedades cardiovasculares ha sido ampliamente estudiado durante muchos años. Numerosos estudios han corroborado que las dietas ricas en frutas y hortalizas (dieta mediterránea) resultan cardiosaludables y que diversas sustancias bioactivas que componen los alimentos tienen un efecto preventivo en diversas enfermedades crónicas como son las enfermedades cardiovasculares. En esta revisión vamos a tratar ciertas sustancias bioactivas, como son algunas incluidas en el grupo de los flavonoides (catequinas y proantocianidinas, antocianinas e isoflavonas), estilbenos como el resveratrol, péptidos bioactivos, esteroles vegetales y ácidos grasos poliinsaturados omega-3.

Palabras clave: Enfermedad cardiovascular. Catequinas. Antocianidinas. Antocianinas. Resveratrol. Omega-3.

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