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Revista Española de Enfermedades Digestivas

Print version ISSN 1130-0108

Rev. esp. enferm. dig. vol.107 n.8 Madrid Aug. 2015




Overt obscure gastrointestinal bleeding secondary to small bowel gastrointestinal stromal tumor diagnosed by videocapsule endoscopy

Tumor de GIST de intestino delgado como causa de hemorragia digestiva de origen oculto manifiesta diagnosticado por cápsula endoscópica



Gabriel Carrilero-Zaragoza1, Guillermo Carbonell-López-del-Castillo2, Gema Ruiz-García3, Juan Egea-Valenzuela1, Paula Tomas-Pujante1, Elena Iglesias-Jorquera1, Josefa Parra-García3, Antonio Sánchez-Torres1, Elena Navarro-Noguera1, Esther Estrella-Díaz1 and Luis Fernando Carballo-Álvarez1

Services of 1Digestive Diseases, 2Radiodiagnosis, and 3Pathology. Hospital Universitario Virgen de la Arrixaca. Murcia, Spain



An 82 year-old male was admitted to our hospital presenting rectal bleeding with hemodynamic and analytic compromise (hemoglobin: 7.3 g/dl). He had personal history of percutaneous closure of the left atrial appendage, severe pulmonary hypertension and was under double-antiaggregation therapy (triflusal and aspirin).

The patient required red blood cells transfusion and upper and lower emergency endoscopies were performed, not being able to find the bleeding lesion. As the origin of the hemorrhage was suspected in the small bowel, videocapsule endoscopy was performed in the following hours, observing a huge jejunal tumor with a big ulcer on its surface (Fig. 1).



Diagnostic study was completed with an abdominal computed tomography in which a 10x5.3 cm tumor was observed in the jejunoileal area, suggestive of lymphoma vs. gastrointestinal stromal tumor (GIST) (Fig. 2).



Once the patient was stable and with no more episodes of bleeding, surgical intervention was carried out to remove the tumor and the affected segment of the small bowel. Histologic examination of the specimen reported a definitive diagnosis of GIST (Fig. 3).




Submucosal tumors have been described as a cause for gastrointestinal bleeding located in the small bowel (1), but it is a rare condition especially in cases of acute bleeding (2).

However, chronic anemia secondary to gastrointestinal occult bleeding is the most frequent form of presentation of GISTs of jejunum and ileum (3,4), as in this case due to ulceration of the mucosa.



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2. Aberle J, Kilie E, Guth S, et al. An unusual cause of acute lower gastrointestinal bleeding. Acta Gastroenterol Belg 2006;69:221-3.         [ Links ]

3. Oyanedel R, O'Brien A, Pizarro A, et al. Tumor estromal gastrointestinal (GIST): formas de presentación. Rev Chil Radiol 2005; 11:13-8.         [ Links ]

4. Bucher P, Egger JF, Gervaz P, et al. An audit of surgical management of gastrointestinal stromal tumours (GIST). Eur J Surg Oncol 2006;32:310-4.         [ Links ]

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