<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0003-3170</journal-id>
<journal-title><![CDATA[Angiología]]></journal-title>
<abbrev-journal-title><![CDATA[Angiología]]></abbrev-journal-title>
<issn>0003-3170</issn>
<publisher>
<publisher-name><![CDATA[Arán Ediciones S.L.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0003-31702023000500002</article-id>
<article-id pub-id-type="doi">10.20960/angiologia.00416</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Estudio coste-efectividad del diagnóstico de trombosis venosa profunda en el medio hospitalario]]></article-title>
<article-title xml:lang="en"><![CDATA[Cost-effectiveness study of deep venous thrombosis diagnosis at the hospital setting]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Díez-Martínez]]></surname>
<given-names><![CDATA[Manuel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[del Blanco-Alonso]]></surname>
<given-names><![CDATA[Isabel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[García-Rivera]]></surname>
<given-names><![CDATA[Elena]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Soriano-Iniesta]]></surname>
<given-names><![CDATA[Joel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Fernández-Bello]]></surname>
<given-names><![CDATA[Sergio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Vaquero-Puerta]]></surname>
<given-names><![CDATA[Carlos]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Clínico Universitario de Valladolid Servicio de Angiología, Cirugía Vascular y Endovascular ]]></institution>
<addr-line><![CDATA[Valladolid ]]></addr-line>
<country>España</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>10</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>10</month>
<year>2023</year>
</pub-date>
<volume>75</volume>
<numero>5</numero>
<fpage>284</fpage>
<lpage>289</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S0003-31702023000500002&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S0003-31702023000500002&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S0003-31702023000500002&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  Introducción y objetivos: la trombosis venosa profunda (TVP) supone una importante carga económica. Nuestro objetivo primario es comparar dos estrategias diagnósticas en cuanto a costes y a efectividad: la prueba del dímero D a todos los pacientes con sospecha con condicionarla a la probabilidad clínica pretest. El secundario, analizar el coste del diagnóstico en nuestro centro y los factores asociados a su presentación.  Material y métodos: estudio prospectivo de los pacientes atendidos con sospecha de TVP de extremidad inferior entre mayo y octubre de 2019. Se analizaron las variables de la escala de Wells, el TEP asociado, el dímero D, el resultado del eco Doppler y los costes (atención en Urgencias, el reactivo del dímero D y la realización de un eco Doppler, obtenidos del Boletín Oficial de la comunidad y de la unidad de cobros del hospital). El análisis estadístico se realizó con SPSS, pruebas de &#967;2 y el test exacto de Fisher.  Resultados: se estudiaron 249 pacientes. 116 (46,59 %) presentaron TVP. La edad media fue de 70 años (21-95). Aquellos con TVP presentaron con más frecuencia: sexo masculino (52,6 % frente a 39,8 %, p = 0,04), cáncer (29,3 % frente a 16,5 %, p = 0,016), dolor (80,2 % frente a 45,1 %, p &lt; 0,001), edema (93,1 % frente a 57,1 %, p &lt; 0,001), empastamiento (72,4 % frente a 14,3 %, p &lt; 0,001), TEP (25,9 % frente a 13,5 %, p = 0,014), menor diagnóstico alternativo (0,9 % frente a 62,4 %, p &lt; 0,001) y menor obesidad (7,8 % frente a 18,8 %, p = 0,011). El gasto generado fue de 192,49 euros por paciente. Para el objetivo primario se analizaron a 144 pacientes (aquellos con dímero D). La estrategia 1 generó un gasto de 190,41 euros por paciente, con una sensibilidad del 100 % y una especificidad del 7,1 %; la estrategia 2, 188,51 euros por paciente, con una sensibilidad del 88,3 % y una especificidad del 78,5 %. Ambas estrategias son un 1 % y un 2 % más económicas que el gasto generado, respectivamente.  Conclusión: la aplicación de algoritmos diagnósticos en las sospechas de TVP es coste-efectiva, por lo que su empleo debería ser generalizado.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Introduction and objective: deep venous thrombosis (DVT) is a significant economic burden. The study primary endpoint is to compare two diagnostic strategies in terms of cost and effectiveness: D-dimer to all patients with suspected DVT vs conditioning it to the pre-test clinical probability; the secondary endpoint is to analyze the cost of DVT diagnosis in our center and the factors associated with its presentation.  Material and methods: this was a prospective study of patients with suspected DVT of lower extremities conducted between May and October 2019. The variables of the Wells scale, associated PTE, D-dimer levels, Doppler echocardiography and costs (emergency care, D-dimer and Doppler echocardiography obtained from the region Official Bulletin and the hospital billing unit) were analyzed. The statistical analysis was performed with SPSS, the chi-square test, and Fisher's exact test.  Results: a total of 249 patients were studied, 116 of whom (46.59 %) presented with DVT. The mean age was 70 years (21-). Those with DVT were predominantly men (52.6 % vs 39.8 %; p = .04), had cancer (29.3 % vs 16.5 %, p = 0.016), pain (80.2 % vs 45.1 %; p &lt; .001), edema (93.1 % vs 57.1 %, p &lt; .001), slurring (72.4 % vs 14.3 %; p &lt; .001), PTE (25.9 % vs 13.5 %, p = .014), less alternative diagnosis (0.9 % vs 62.4 %; p = .001) and less obesity (7.8 % vs 18.8 %; p = .011). The cost generated was &#8364; 192.49 per patient. Regarding the primary endpoint, 144 patients (those with D-dimer) were analyzed. Strategy #1 resulted in a cost of &#8364;190.41 per patient with 100 % sensitivity and 7.1 % specificity; strategy # 2, resulted in a cost of &#8364;188.51/patient, with 88.3 % and 78.5 % sensitivity and specificity rates, respectively. Both strategies are 1 % and 2 % cheaper than the cost generated.  Conclusion: the application of diagnostic algorithms for suspected DVT is cost-effective, so its use should be generalized.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Trombosis venosa profunda]]></kwd>
<kwd lng="es"><![CDATA[Diagnóstico]]></kwd>
<kwd lng="es"><![CDATA[Coste]]></kwd>
<kwd lng="es"><![CDATA[Efectividad]]></kwd>
<kwd lng="en"><![CDATA[Deep venous thrombosis]]></kwd>
<kwd lng="en"><![CDATA[Diagnosis]]></kwd>
<kwd lng="en"><![CDATA[Cost]]></kwd>
<kwd lng="en"><![CDATA[Effectiveness]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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