<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1134-8046</journal-id>
<journal-title><![CDATA[Revista de la Sociedad Española del Dolor]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Soc. Esp. Dolor]]></abbrev-journal-title>
<issn>1134-8046</issn>
<publisher>
<publisher-name><![CDATA[Inspira Network Group, S.L ]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1134-80462017000200074</article-id>
<article-id pub-id-type="doi">10.20986/resed.2016.3485/2016</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Eficacia de las inyecciones intrarticulares de ácido hialurónico para el tratamiento de la artrosis de rodilla: resultados de una serie de casos tratados en una Unidad del Dolor]]></article-title>
<article-title xml:lang="en"><![CDATA[Effectiveness of intra-articular injections of hyaluronic acid for the treatment of knee osteoarthritis: results of a series of patients treated in a pain unit]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodrigo-Royo]]></surname>
<given-names><![CDATA[M. D.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Quero-López]]></surname>
<given-names><![CDATA[J. C.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Aparicio-Abiol]]></surname>
<given-names><![CDATA[R. M.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Cía-Blasco]]></surname>
<given-names><![CDATA[P.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Baltanás-Rubio]]></surname>
<given-names><![CDATA[P.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Acín-Lázaro]]></surname>
<given-names><![CDATA[M. P.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Universitario Lozano Blesa Unidad del Dolor ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Royo Villanova Servicio de Anestesiología ]]></institution>
<addr-line><![CDATA[Zaragoza ]]></addr-line>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>04</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>04</month>
<year>2017</year>
</pub-date>
<volume>24</volume>
<numero>2</numero>
<fpage>74</fpage>
<lpage>84</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S1134-80462017000200074&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S1134-80462017000200074&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S1134-80462017000200074&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Objetivo:  Valorar los resultados del tratamiento de la artrosis de rodilla mediante una inyección intrarticular de ácido hialurónico en lo que se refiere a reducción del dolor, mejoría de la función articular y duración de los efectos.  Método:  Pacientes con diagnóstico clínico y radiológico de artrosis en diferentes fases de evolución en una o ambas rodillas, tratados en la Unidad del Dolor de un hospital de tercer nivel. Se recogió prospectivamente la información facilitada por el paciente siguiendo la práctica clínica habitual: características sociodemográficas y clínicas. Se realizaron valoraciones pre y postratamiento del dolor en reposo, a la deambulación y al subir/bajar escaleras, rigidez matutina, tiempo caminando y las horas/calidad del descanso nocturno. En la visita postratamiento se registraron, además, el grado de mejoría experimentada, duración de la misma y la satisfacción del investigador. El tratamiento consistió en una única inyección de ácido hialurónico por vía intrarticular, con posibilidad de una dosis de recuerdo.  Resultados:  Se incluyeron 29 pacientes (52 rodillas); en 23 se trataron ambas rodillas (n = 46) y en 6 una rodilla. El 92,3 % corresponden a articulaciones artrósicas con un tiempo de evolución &gt; 12 meses, con grado clínico 4-5 en el 61,6 % de las rodillas tratadas (n = 32) y grado radiológico III-IV de Kellgren y Lawrence en el 67,7 % (n = 35), por lo que un 55,8 % de los casos fueron calificados como severos por los investigadores. Hubo una mejoría significativa en todos los parámetros de dolor y funcionalidad considerados (p &lt; 0,001). El tiempo caminando se incrementó en más del 100 % y el 67,3 % de los pacientes definieron su calidad de sueño como normal, frente al 38,5 % inicial. La mejoría fue valorada por el investigador como buena o muy buena en el 73,1 % de los casos.  Conclusiones:  Nuestro trabajo confirma la eficacia de una única inyección de ácido hialurónico para reducir la sintomatología en pacientes con gonartrosis en diferentes grados de severidad, con resultados que se mantienen entre 6 y 12 meses y son especialmente significativos en aquellos con artrosis leve y moderada.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Objective:  To evaluate the results of treatment of knee osteoarthritis with a single intra-articular injection of hyaluronic acid in terms of pain reduction, joint function improvement and duration of effects.  Method:  Patients with clinical and radiological diagnosis of osteoarthritis at different stages of evolution in one or both knees were treated at the Pain Unit of a tertiary hospital. Sociodemographic and clinical characteristics provided by the patient following the usual clinical practice were prospectively collected. Pain at rest, walking, up and down stairs, morning stiffness, time walking as well as time/quality sleep were recorded pre and post-treatment. At post-treatment visit the degree and duration of improvement experienced, as well as the investigator assessment were also recorded. The treatment consisted of a single intra-articular injection of hyaluronic acid, with the possibility of a booster.  Results:  A total of 29 patients (52 knees) were included. Both knees were treated in 23 of them (n = 46) and only one knee in the remaining 6. The 92.3 % were osteoarthritic joints with an evolution &gt; 12 months, with clinical grade 4-5 in 61.6 % (n = 32) and radiological grade III-IV of Kellgren &amp; Lawrence in 67.7 % (n = 35), making 55.8 % of cases were classified as severe by the investigators. There was a significant improvement in all parameters of pain and function considered (p &lt; 0.001). Walking time increased by over 100 % and 67.3 % of patients defined their quality of sleep as normal, compared to 38.5 % at baseline. The improvement was assessed by the investigator as good or very good in 73.1 % of cases.  Conclusions:  Our study confirms the effectiveness of a single injection of hyaluronic acid to reduce symptoms in patients with knee osteoarthritis with different grades of severity, with results that remain between 6 and 12 months and are especially significant in those patients with mild to moderate osteoarthritis.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Knee osteoarthritis]]></kwd>
<kwd lng="en"><![CDATA[hyaluronic acid]]></kwd>
<kwd lng="es"><![CDATA[Gonartrosis]]></kwd>
<kwd lng="es"><![CDATA[ácido hialurónico]]></kwd>
</kwd-group>
</article-meta>
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