1134-8046 1134-8046 S1134-80462018000100062 10.20986/resed.2017.3584/2017 España España 00 02 2018 00 02 2018 25 1 62 63 2011 14 2 2 E103-17 2016 17 3 3 FDA 2011 2014 160 1 1 38-47