<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1135-5727</journal-id>
<journal-title><![CDATA[Revista Española de Salud Pública]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Esp. Salud Publica]]></abbrev-journal-title>
<issn>1135-5727</issn>
<publisher>
<publisher-name><![CDATA[Ministerio de Sanidad]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1135-57272018000100208</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Impacto de la transmisión nosocomial del virus de la gripe en un hospital de agudos]]></article-title>
<article-title xml:lang="en"><![CDATA[Impact of nosocomial transmission of influenza virus in an acute hospital]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mendoza-García]]></surname>
<given-names><![CDATA[José L]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Quirós-González]]></surname>
<given-names><![CDATA[Víctor]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Jiménez-Rodríguez]]></surname>
<given-names><![CDATA[Mar]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Haro-Pérez]]></surname>
<given-names><![CDATA[Ana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gutiérrez Zufiaurre]]></surname>
<given-names><![CDATA[Mª. Nieves]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez-Pérez]]></surname>
<given-names><![CDATA[Paz]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Universitario de Salamanca Servicio de Medicina Preventiva ]]></institution>
<addr-line><![CDATA[ Castilla y León]]></addr-line>
<country>España</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Universitario de Salamanca Servicio de Microbiología ]]></institution>
<addr-line><![CDATA[ Castilla y León]]></addr-line>
<country>España</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2018</year>
</pub-date>
<volume>92</volume>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S1135-57272018000100208&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S1135-57272018000100208&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S1135-57272018000100208&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Fundamentos: El incremento de la morbimortalidad asociado a la infección por el virus de la gripe supone un importante reto a nivel mundial, con especial relevancia dentro de las instituciones sanitarias. El objetivo del estudio fue analizar el impacto, repercusiones y características de la transmisión nosocomial del virus de la gripe.  Métodos: Se incluyó una muestra de 286 pacientes hospitalizados en un centro de tercer nivel con gripe con firmada (ARN del virus en muestras respiratorias). El di seño del estudio fue observacional, mediante recogida de los resultados microbiológicos positivos de la temporada de gripe 2016-2017. Se realizó un análisis estadístico comparativo entre los casos de gripe comunitaria y los casos nosocomiales.  Resultados: El 14.3% del total de la muestra (41 casos) se consideró de origen nosocomial. Se observaron diferencias significativas en el porcentaje de vacunados entre los casos de infección nosocomial (34,1%) y comunitaria (50,2%), y en el número de días de ingreso tras diagnóstico (12 ±22 días para los casos nosocomiales y 6 ±8 días para los comunitarios). La tasa de ataque fue del 0,66%.  Conclusiones: La adquisición nosocomial del virus de la gripe se tradujo en una mayor gravedad del cuadro y en el incremento de los días de estancia hospitalaria. El estricto cumplimiento de las medidas de control y vigilancia epidemiológica de los casos de gripe ha permitido lograr una tasa de ataque reducida.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Background: The increase in morbidity and mortality associated the influenza virus infections represents an important global challenge, with particular relevance within health institutions. The aim of the study was to highlight the impact, repercussions and characteristics of the nosocomial transmission of influenza virus.  Methods: A sample of 286 hospitalized patients in a third-level hospital with confirmed influenza (virus RNA in respiratory specimens) is included. The study design was observational, through the collection of positive microbiological results from the 2016-2017 season. A comparative statistical analysis was carried out between cases of community-acquired influenza and hospital-acquired cases.  Results: 14.3% of the total sample (41 cases) was considered of nosocomial origin. Significant differences were observed in the percentage of vaccinated between hospital-acquired (34.1%) and community-acquired (50.2%); and in the number of days of hospitalization after diagnosis between both groups. The attack rate was 0.66%.  Conclusions: The nosocomial acquisition of the influenza virus resulted in a greater severity of the process and in the increase of days of hospital stay. Strict adherence to control measures and epidemiological surveillance of influenza cases has allowed to reduce the attack rate.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Infección hospitalaria]]></kwd>
<kwd lng="es"><![CDATA[Virus de la Influenza A]]></kwd>
<kwd lng="es"><![CDATA[Vacunas contra la Influenza]]></kwd>
<kwd lng="es"><![CDATA[Vacunas]]></kwd>
<kwd lng="es"><![CDATA[Control de infecciones]]></kwd>
<kwd lng="es"><![CDATA[Reacción en Cadena de la Polimerasa]]></kwd>
<kwd lng="en"><![CDATA[Cross infection]]></kwd>
<kwd lng="en"><![CDATA[Influenza A virus]]></kwd>
<kwd lng="en"><![CDATA[Influenza Vaccines]]></kwd>
<kwd lng="en"><![CDATA[Vaccines]]></kwd>
<kwd lng="en"><![CDATA[Infection Control]]></kwd>
<kwd lng="en"><![CDATA[Polymrase Chain Reaction]]></kwd>
</kwd-group>
</article-meta>
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<name>
<surname><![CDATA[Giannetta]]></surname>
<given-names><![CDATA[ET]]></given-names>
</name>
<name>
<surname><![CDATA[Hayden]]></surname>
<given-names><![CDATA[FG]]></given-names>
</name>
<name>
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<given-names><![CDATA[BM]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Preventing nosocomial influenza by improving the vaccine acceptance rate of clinicians]]></article-title>
<source><![CDATA[Infect Control Hosp Epidemiol]]></source>
<year>2004</year>
<volume>25</volume>
<numero>11</numero>
<issue>11</issue>
<page-range>923-8</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
