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<front>
<journal-meta>
<journal-id>1137-6627</journal-id>
<journal-title><![CDATA[Anales del Sistema Sanitario de Navarra]]></journal-title>
<abbrev-journal-title><![CDATA[Anales Sis San Navarra]]></abbrev-journal-title>
<issn>1137-6627</issn>
<publisher>
<publisher-name><![CDATA[Gobierno de Navarra. Departamento de Salud]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1137-66272015000200018</article-id>
<article-id pub-id-type="doi">10.4321/S1137-66272015000200018</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[La espirometría en preescolares]]></article-title>
<article-title xml:lang="en"><![CDATA[The spirometry in pre-school children]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Pedrosa]]></surname>
<given-names><![CDATA[M.]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Quirce]]></surname>
<given-names><![CDATA[S.]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
</contrib-group>
<aff id="A01">
<institution><![CDATA[,Hospital La Paz Servicio de Alergología ]]></institution>
<addr-line><![CDATA[Madrid ]]></addr-line>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>08</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>08</month>
<year>2015</year>
</pub-date>
<volume>38</volume>
<numero>2</numero>
<fpage>325</fpage>
<lpage>327</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S1137-66272015000200018&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S1137-66272015000200018&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S1137-66272015000200018&amp;lng=en&amp;nrm=iso"></self-uri></article-meta>
</front><body><![CDATA[ 
<a name="top"></a>    <p><font face="Verdana" size="2"><b>CARTAS/OPINIÓN</b></font></p>
    <p>&nbsp;</p>
    <p><font face="Verdana" size="4"><b>La espirometría en preescolares</b></font></p>
    <p><font face="Verdana" size="4"><b>The spirometry in pre-school children</b></font></p>
    <p>&nbsp;</p>
    <p>&nbsp;</p>
    <p><font face="Verdana" size="2"><a href="#bajo">Direcci&oacute;n para correspondencia</a></font></p>
    <p>&nbsp;</p>
    <p>&nbsp;</p>
    ]]></body>
<body><![CDATA[<p><font face="Verdana" size="2"><b>Sr. Director:</b></font></p>
    <p><font face="Verdana" size="2">El asma es una enfermedad de distribución mundial que se estima que afecta a 300 millones de personas. La prevalencia de esta enfermedad va en aumento. Hay varias explicaciones que se han propuesto como responsables de este incremento en la prevalencia: exposición al humo del tabaco, contaminación del aire, cambios en la dieta, obesidad y las infecciones<sup>1</sup>. No obstante, el hecho de que haya una conciencia creciente del impacto que tienen las enfermedades respiratorias puede haber contribuido también a un mayor diagnóstico por parte de los profesionales sanitarios. Sin embargo, no todos los casos que se etiquetan como asma realmente lo son. Para evitar esto, las guías internacionales recomiendan que el diagnóstico de asma se base tanto en la presencia de síntomas como en medidas objetivas de una obstrucción variable al flujo aéreo<sup>2</sup>. La espirometría con prueba broncodilatadora tiene, por tanto, un elevado valor diagnóstico, aunque no siempre se realice, y esto es causa de muchos diagnósticos erróneos. Esto ha quedado demostrado en varios estudios en los que se ha reevaluado pacientes con un diagnóstico previo de asma y éste se excluyó en un 30-41% de los casos<sup>3-5</sup>.</font></p>
    <p><font face="Verdana" size="2">El hecho de no realizar espirometrías es particularmente frecuente en el caso de niños preescolares<sup>6</sup> puesto que se asume que esta población no es capaz de alcanzar los requerimientos de calidad propuestos para la aceptación de esta exploración. Sin embargo, los espirómetros actuales disponen de sistemas de incentivación y criterios modificados para la aceptabilidad y reproducibilidad, lo que permite realizar pruebas de función pulmonar en niños preescolares por personal entrenado.</font></p>
    <p><font face="Verdana" size="2">Las indicaciones de realización de espirometría en niños con patología respiratoria incluyen la tos crónica, los sibilantes persistentes<sup>7</sup> y el diagnóstico y monitorización del asma<sup>8,9</sup> y la fibrosis quística<sup>10,11</sup>.</font></p>
    <p><font face="Verdana" size="2">Los parámetros que se valoran en la espirometría son FEV<sub>1</sub>, FVC y el cociente FEV<sub>1</sub>/FVC, al igual que en adultos. El cociente FEV<sub>1</sub>/FVC es el parámetro más sensible y específico para identificar la obstrucción aérea. Estos parámetros se comparan con los valores de referencia de la población normal, aunque son pocos los países que disponen de valores de referencia para la población infantil<sup>12-15</sup>. La variación en el FEV<sub>1</sub> es altamente específica para el diagnóstico de asma en niños con síntomas inespecíficos de la vía respiratoria inferior<sup>16</sup>. Además permite clasificar la gravedad del asma, y tiene utilidad para predecir las exacerbaciones<sup>17</sup>, la progresión de la enfermedad y el deterioro funcional de la calidad de vida. Una baja función pulmonar al nacimiento se asocia con un elevado riesgo de padecer asma a la edad de 10 años<sup>18</sup>. Por este motivo se debe insistir en la realización de medidas de función pulmonar objetivas en los niños, ya que esto permite predecir el curso de la enfermedad.</font></p>
    <p><font face="Verdana" size="2">Diversos autores han demostrado que los niños preescolares entre 2 y 6 años son capaces de realizar maniobras espirométricas aceptables en un 55-82% de los casos<sup>19-21</sup>. A estos estudios hay que sumar los recientemente publicados en la revista Anales del Sistema Sanitario de Navarra por Olaguibel y col<sup>22</sup>. El estudio incluyó 114 niños preescolares sanos de los que 93 aceptaron participar en la realización de pruebas de función pulmonar. De ellos en 60 niños obtuvieron maniobras aceptables y reproducibles y en otros 16 se obtuvieron al menos dos maniobras aceptables, aunque no cumplían criterios de reproducibilidad. En los pacientes en los que las espirometrías no fueron exitosas el error más común fue la terminación prematura de la maniobra (39% de los casos) y un pico flujo inadecuado (30%). Este estudio demuestra que, a pesar de haber utilizado criterios de calidad exigentes y sobre una población sana no entrenada previamente, en el 59% de los niños preescolares se pueden obtener espirometrías forzadas de calidad. Por lo tanto, puesto que técnicamente la exploración funcional respiratoria es posible en niños preescolares y dadas las implicaciones diagnósticas, de seguimiento y pronósticas que tiene la medición de la función pulmonar desde edades tempranas, se debe fomentar la realización de exploración funcional en niños con patología respiratoria.</font></p>
    <p>&nbsp;</p>
    <p align="right"><font face="Verdana" size="2"><b>M. Pedrosa y S. Quirce</b>    <br>Servicio de Alergología, Hospital La Paz, Madrid.</font></p>
    <p>&nbsp;</p>
    ]]></body>
<body><![CDATA[<p><font face="Verdana" size="2"><b>Bibliografía</b></font></p>
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Aurora P, Stocks J, Oliver C, Saunders C, Castle R, Chaziparasidis G, et al. Quality control for spirometry in preschool children with and without lung disease. Am J Respir Crit Care Med 2004; 169: 1152-1159.    &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[&#160;<a href="javascript:void(0);" onclick="javascript: window.open('/scielo.php?script=sci_nlinks&ref=427092&pid=S1137-6627201500020001800021&lng=','','width=640,height=500,resizable=yes,scrollbars=1,menubar=yes,');">Links</a>&#160;]<!-- end-ref --></font></p>    <!-- ref --><p><font face="Verdana" size="2">22. Olaguíbel Rivera J, Álvarez Puebla M, Vela Vizcaíno C, Cambra Contín K, Uribe San Martín M, de Esteban Chocarro B. Calidad de la espirometría en preeescolares. An Sist Sanit Navar 2014; 37: 81-89.    &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[&#160;<a href="javascript:void(0);" onclick="javascript: window.open('/scielo.php?script=sci_nlinks&ref=427094&pid=S1137-6627201500020001800022&lng=','','width=640,height=500,resizable=yes,scrollbars=1,menubar=yes,');">Links</a>&#160;]<!-- end-ref --></font></p>
    <p>&nbsp;</p>
    <p>&nbsp;</p>
    <p><font face="Verdana" size="2"><a href="#top"><img border="0" src="/img/revistas/asisna/v38n2/seta.gif" width="15" height="17"></a><a name="bajo"></a><b>Direcci&oacute;n para correspondencia:</b>    <br>Santiago Quirce    <br>Servicio de Alergología    ]]></body>
<body><![CDATA[<br>Hospital de La Paz    <br>P<sup>o</sup> de la Castellana, 261    <br>28046 Madrid    <br><a href="mailto:squirce@gmail.com">squirce@gmail.com</a></font></p>
     ]]></body><back>
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