<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1137-6627</journal-id>
<journal-title><![CDATA[Anales del Sistema Sanitario de Navarra]]></journal-title>
<abbrev-journal-title><![CDATA[Anales Sis San Navarra]]></abbrev-journal-title>
<issn>1137-6627</issn>
<publisher>
<publisher-name><![CDATA[Gobierno de Navarra. Departamento de Salud]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1137-66272022000300011</article-id>
<article-id pub-id-type="doi">10.23938/assn.1027</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Higiene con clorhexidina en unidades de cuidados intensivos para prevenir infecciones nosocomiales. Revisión sistemática]]></article-title>
<article-title xml:lang="en"><![CDATA[Chlorhexidine bathing in intensive care units for the prevention of nosocomial infections. A systematic review]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Esarte]]></surname>
<given-names><![CDATA[Jon]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mujika]]></surname>
<given-names><![CDATA[Agurtzane]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad del País Vasco Facultad de Medicina y Enfermería Departamento de Enfermería II]]></institution>
<addr-line><![CDATA[San Sebastián ]]></addr-line>
<country>España</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2022</year>
</pub-date>
<volume>45</volume>
<numero>3</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S1137-66272022000300011&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S1137-66272022000300011&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S1137-66272022000300011&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen El objetivo de este estudio fue conocer la efectividad de la higiene con clorhexidina para prevenir infecciones nosocomiales en pacientes adultos ingresados en unidades de cuidados intensivos (UCI). Se realizó una revisión sistemática de los ensayos clínicos aleatorizados publicados en los últimos 10 años en diferentes bases de datos. Se extrajo información sobre distintos tipos de infecciones, mortalidad, microorganismos implicados y microorganismos multirresistentes. Se incluyeron cinco estudios. La intervención no fue efectiva en dos estudios debido a una baja frecuencia de infecciones y a una alta prevalencia de bacterias gramnegativas, frente a las que la clorhexidina no es tan eficaz. La intervención tampoco redujo las tasas de mortalidad. La intervención fue efectiva principalmente para prevenir bacteriemias e infecciones por bacterias grampositivas, por lo que podría ser útil en las UCI con altas prevalencias de infecciones de esas características.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract The aim of this study was to determine the effectiveness of chlorhexidine use patients in adult intensive care units for preventing nosocomial infections. We carried out a systematic review of randomized clinical trials published over the past 10 years. We collected the following data: type of infection, mortality, isolated microorganisms, and multi-drug-resistant microorganisms. In two out of the five studies included in the review, bathing with chlorhexidine was ineffective due to low cross-infection rates at baseline and Gram-negative bacteria being the most prevalent type of microorganism, against which chlorhexidine is not as effective. No decline in death rates was either observed. Chlorhexidine bathing was mainly effective in preventing bloodstream infections and those caused by Gram-positive bacteria. Thus, its use may be effective in intensive care units with high prevalence of infections by this type of microorganisms.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Unidades de Cuidados Intensivos]]></kwd>
<kwd lng="es"><![CDATA[Clorhexidina]]></kwd>
<kwd lng="es"><![CDATA[Baños]]></kwd>
<kwd lng="es"><![CDATA[Higiene]]></kwd>
<kwd lng="es"><![CDATA[Infección hospitalaria]]></kwd>
<kwd lng="en"><![CDATA[Intensive Care units]]></kwd>
<kwd lng="en"><![CDATA[Chlorhexidine]]></kwd>
<kwd lng="en"><![CDATA[Baths]]></kwd>
<kwd lng="en"><![CDATA[Hygiene]]></kwd>
<kwd lng="en"><![CDATA[Nosocomial infection]]></kwd>
</kwd-group>
</article-meta>
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