<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1139-7632</journal-id>
<journal-title><![CDATA[Pediatría Atención Primaria]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Pediatr Aten Primaria]]></abbrev-journal-title>
<issn>1139-7632</issn>
<publisher>
<publisher-name><![CDATA[Asociación Española de Pediatría de Atención Primaria]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1139-76322018000300002</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Presentación clínica y tratamiento de los niños hospitalizados por gripe durante cinco temporadas]]></article-title>
<article-title xml:lang="en"><![CDATA[Clinical presentation and treatment of children hospitalised due to influenza from the 2012 to the 2016 season]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sánchez Bayle]]></surname>
<given-names><![CDATA[Marciano]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Villalobos Pinto]]></surname>
<given-names><![CDATA[Enrique]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Manso Cuevas]]></surname>
<given-names><![CDATA[Mª Araceli]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Palomino Pérez]]></surname>
<given-names><![CDATA[Laura]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Juan Bitria]]></surname>
<given-names><![CDATA[Ester de]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Infantil Universitario Niño Jesús  ]]></institution>
<addr-line><![CDATA[Madrid ]]></addr-line>
<country>España</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Infantil Universitario Niño Jesús  ]]></institution>
<addr-line><![CDATA[Madrid ]]></addr-line>
<country>España</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>09</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>09</month>
<year>2018</year>
</pub-date>
<volume>20</volume>
<numero>79</numero>
<fpage>e61</fpage>
<lpage>e67</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S1139-76322018000300002&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S1139-76322018000300002&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S1139-76322018000300002&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  Objetivo: estudiar las características clínicas y demográficas, así como el uso de oseltamivir, de los niños hospitalizados por gripe en un hospital pediátrico terciario.  Pacientes y métodos:  estudio descriptivo observacional de niños entre 0 y 18 años ingresados en las temporadas de diciembre a mayo de 2012 a 2017 con diagnóstico confirmado microbiológicamente de gripe.  Resultados:  Se han estudiado 166 pacientes. El porcentaje de ingresos sobre el total de ingresados en las mismas fechas osciló entre el 2,03 y el 9,69%. El mayor número de ingresos fueron en la penúltima temporada de estudio (p&lt;0,0001). Los niños diagnosticados de gripe A presentaron una edad menor que los que lo fueron de gripe B (2,45 frente a 3,88 años, p&lt;0,0001), no encontrándose diferencias significativas en cuanto al sexo, los días de estancia media, la necesidad de antibioterapia o de broncodilatadores. Recibieron tratamiento con oseltamivir un total de 96 niños (57,83%), 75 de ellos en la temporada 2015-2016. No se encontraron diferencias en las características de los niños que lo recibieron frente a los que no. La estancia media global fue 0,89 días mayor en aquellos niños que recibieron el antiviral, diferencia casi significativa en el total de la muestra ( p = 0,052), durante la temporada 2015-2016 la duración fue 1,8 días mayor (p = 0,039). No se encontraron diferencias significativas en cuanto al porcentaje de pacientes con neumonía ni de los que precisaron ingreso en la Unidad de Cuidados Intensivos Pediátricos entre los tratados respecto a los no tratados.  Conclusiones:  el porcentaje de niños ingresados por gripe es importante, habiéndose incrementado en la última temporada. Los niños diagnosticados con gripe A tienen una edad significativamente menor que los que presentaron gripe B. En nuestro caso no se encontraron ventajas en el tratamiento con oseltamivir.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Objective: to analyse the demographic and clinical characteristics and the use of oseltamivir in children admitted with influenza to a tertiary care children&#8217;s hospital.  Patients and methods: we conducted a descriptive observational study of all patients aged 0 to 18 years admitted in every December-to-May epidemic season between 2012 and 2016 with a microbiological diagnosis of influenza.  Results: we reviewed the cases of 166 patients. The percentage of influenza admissions out of the total admissions during the seasons under study between 2.03% and 9.69%. The highest number of admissions occurred in the second to last season under study (p &lt; .0001). Children with infection by influenza A were younger compared to those with influenza B (2.45 vs. 3.88 years, p&lt; .0001), and we found no significant differences between serotypes in the sex distribution, mean length of stay or need for antibiotherapy or bronchodilators. A total of 96 children (57.83%) received oseltamivir, 75 of them in the 2015-2016 season. We found no differences in the characteristics of children treated with oseltamivir compared to those that were not. The mean length of stay was 0.89 days overall and was greater in children treated with the antiviral drug, with p-values that neared the threshold for significance in the entire sample (p = .052); the length of stay was 1.8 days longer in the 2015-2016 season (p = .039). We did not find significant differences between patients that received oseltamivir and patients that did not in the percentage that developed pneumonia or the percentage that required admission to the paediatric intensive care unit.  Conclusions:  the percentage of children admitted with influenza virus was substantial and increased in the last season. Children with an influenza A diagnosis were younger compared to children with influenza B. Our study did not find advantages in the use of oseltamivir.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Oseltamivir]]></kwd>
<kwd lng="es"><![CDATA[Virus de la influenza A]]></kwd>
<kwd lng="es"><![CDATA[Virus de la influenza B]]></kwd>
<kwd lng="en"><![CDATA[Oseltamivir]]></kwd>
<kwd lng="en"><![CDATA[Influenza A virus]]></kwd>
<kwd lng="en"><![CDATA[Influenza B virus]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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