<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1139-7632</journal-id>
<journal-title><![CDATA[Pediatría Atención Primaria]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Pediatr Aten Primaria]]></abbrev-journal-title>
<issn>1139-7632</issn>
<publisher>
<publisher-name><![CDATA[Asociación Española de Pediatría de Atención Primaria]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1139-76322018000400017</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Aspectos metodológicos del metaanálisis (2)]]></article-title>
<article-title xml:lang="en"><![CDATA[Methodological aspects of meta-analysis (2)]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Molina Arias]]></surname>
<given-names><![CDATA[Manuel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
<xref ref-type="aff" rid="Ab "/>
<xref ref-type="aff" rid="Af1"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Universitario La Paz Servicio de Gastroenterología Pediátrica ]]></institution>
<addr-line><![CDATA[Madrid ]]></addr-line>
<country>España</country>
</aff>
<aff id="A1b">
<institution><![CDATA[,Asociación Española de Pediatria Comité de Pedriatría Basada en la Evidencia ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>España</country>
</aff>
<aff id="A1c">
<institution><![CDATA[,Asociación Española de Pediatria Atención Primaria  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>España</country>
</aff>
<aff id="A1d">
<institution><![CDATA[,Ciencia sin seso  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>España</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2018</year>
</pub-date>
<volume>20</volume>
<numero>80</numero>
<fpage>401</fpage>
<lpage>405</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S1139-76322018000400017&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S1139-76322018000400017&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S1139-76322018000400017&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  El metaanálisis es un resumen de síntesis cuantitativa habitualmente empleado para analizar los resultados de los estudios primarios de una revisión sistemática. Para que sus conclusiones tengan validez, debe aplicarse la metodología de elaboración de forma correcta y prestarse especial atención a la realización de la revisión, combinando los estudios de forma adecuada y representando los resultados de forma correcta. Revisaremos de forma detallada los aspectos relacionados con los métodos para combinar los estudios primarios y con la interpretación del diagrama de efectos (forest plot), finalizando con algunas recomendaciones para la interpretación de los resultados del metaanálisis.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  A meta-analysis is a summary of quantitative synthesis usually used to analyze the results of the primary studies of a systematic review. In order for its conclusions to be valid, its methodology must be correctly applied, paying special attention to carrying out the bibliographical search, combining the studies in an appropriate manner and representing the results correctly. We will review in detail the aspects related to the methods to combine the primary studies and to the interpretation of the forest plot, ending with some recommendations for the interpretation of the results of the meta-analysis.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Diagrama de efectos]]></kwd>
<kwd lng="es"><![CDATA[Metaanálisis]]></kwd>
<kwd lng="es"><![CDATA[Modelo de efectos aleatorios]]></kwd>
<kwd lng="es"><![CDATA[Modelos de efecto fijo]]></kwd>
<kwd lng="es"><![CDATA[Revisión]]></kwd>
<kwd lng="en"><![CDATA[Review]]></kwd>
<kwd lng="en"><![CDATA[Meta-analysis]]></kwd>
<kwd lng="en"><![CDATA[Random-effects model]]></kwd>
<kwd lng="en"><![CDATA[Fixed-effect model]]></kwd>
<kwd lng="en"><![CDATA[Forest plot]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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