<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1139-7632</journal-id>
<journal-title><![CDATA[Pediatría Atención Primaria]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Pediatr Aten Primaria]]></abbrev-journal-title>
<issn>1139-7632</issn>
<publisher>
<publisher-name><![CDATA[Asociación Española de Pediatría de Atención Primaria]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1139-76322020000400009</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Importancia del diagnóstico y tratamiento precoz de la encefalitis herpética]]></article-title>
<article-title xml:lang="en"><![CDATA[Importance of early diagnosis and treatment of herpetic encephalitis]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gutiérrez Sánchez]]></surname>
<given-names><![CDATA[Aída Mª]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[López Rojo]]></surname>
<given-names><![CDATA[Myriam]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Marín Andrés]]></surname>
<given-names><![CDATA[Marta]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Guerrero Laleona]]></surname>
<given-names><![CDATA[Carmelo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Bustillo Alonso]]></surname>
<given-names><![CDATA[Matilde]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Infantil Universitario Miguel Servet Servicio de Pediatría ]]></institution>
<addr-line><![CDATA[Zaragoza ]]></addr-line>
<country>España</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Universitario Miguel Servet  ]]></institution>
<addr-line><![CDATA[Zaragoza ]]></addr-line>
<country>España</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital Universitario Miguel Servet Servicio de Pediatría Unidad de Infectología Pediátrica]]></institution>
<addr-line><![CDATA[Zaragoza ]]></addr-line>
<country>España</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>09</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>09</month>
<year>2020</year>
</pub-date>
<volume>22</volume>
<numero>87</numero>
<fpage>133</fpage>
<lpage>138</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S1139-76322020000400009&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S1139-76322020000400009&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S1139-76322020000400009&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[ Resumen El virus del herpes simple (VHS) produce una encefalitis necrotizante aguda, afectando típicamente al lóbulo temporal. La existencia de un fármaco antiviral específico, así como el uso de medicación adyuvante como la corticoterapia, han mejorado el pronóstico de las infecciones graves. El retraso en el inicio del tratamiento con aciclovir es un factor claramente relacionado con mala evolución, así como las pautas cortas de tratamiento que se han asociado con mayor riesgo de recidivas.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ Abstract Herpes simplex virus (HSV) causes acute necrotizing encephalitis, typically affecting the temporal lobe. The existence of a specific antiviral drug as well as the use of adjuvant medication such as corticotherapy, have improved the prognosis of severe infections. The delay in the start of treatment with acyclovir is a factor clearly related to poor evolution, as well as short treatment guidelines that have been associated with an increased risk of recurrence.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Aciclovir]]></kwd>
<kwd lng="es"><![CDATA[Encefalitis]]></kwd>
<kwd lng="es"><![CDATA[Virus del herpes simple]]></kwd>
<kwd lng="en"><![CDATA[Acyclovir]]></kwd>
<kwd lng="en"><![CDATA[Encephalitis]]></kwd>
<kwd lng="en"><![CDATA[Herpes simplex virus]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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