<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1139-7632</journal-id>
<journal-title><![CDATA[Pediatría Atención Primaria]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Pediatr Aten Primaria]]></abbrev-journal-title>
<issn>1139-7632</issn>
<publisher>
<publisher-name><![CDATA[Asociación Española de Pediatría de Atención Primaria]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1139-76322020000400016</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Fallo hepático agudo por gripe A: manifestación poco común de un problema frecuente]]></article-title>
<article-title xml:lang="en"><![CDATA[Acute liver failure by Influenza A: rare manifestation of a common problem]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Camacho Arias]]></surname>
<given-names><![CDATA[Mónica]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Portillo Sánchez-Portal]]></surname>
<given-names><![CDATA[María]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez Martínez]]></surname>
<given-names><![CDATA[Alicia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ordóñez Sáez]]></surname>
<given-names><![CDATA[Olga]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Carabaño Aguado]]></surname>
<given-names><![CDATA[Iván]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Medina Benítez]]></surname>
<given-names><![CDATA[Enrique]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Universitario 12 de Octubre Servicio de Pediatría ]]></institution>
<addr-line><![CDATA[Madrid ]]></addr-line>
<country>España</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Universitario 12 de Octubre Servicio de Pediatría Sección de Gastroenterología, Hepatología y Nutrición infantil]]></institution>
<addr-line><![CDATA[Madrid ]]></addr-line>
<country>España</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital Universitario 12 de Octubre Servicio de Pediatría Sección de Cuidados Intensivos Pediátricos]]></institution>
<addr-line><![CDATA[Madrid ]]></addr-line>
<country>España</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Hospital Universitario 12 de Octubre Servicio de Pediatría Sección de Gastroenterología, Hepatología y Nutrición Pediátrica]]></institution>
<addr-line><![CDATA[Madrid ]]></addr-line>
<country>España</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>09</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>09</month>
<year>2020</year>
</pub-date>
<volume>22</volume>
<numero>87</numero>
<fpage>147</fpage>
<lpage>151</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S1139-76322020000400016&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S1139-76322020000400016&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S1139-76322020000400016&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen El fallo hepático agudo es un cuadro grave y poco frecuente en Pediatría. Precisa un manejo multidisplinar. Aunque en la mitad de los casos no se llega a un diagnóstico etiológico definitivo, conviene conocer sus causas según los grupos de edad, debido a su implicación pronóstica y terapéutica. Se reconocen principalmente causas infecciosas, tóxicas, metabólicas y autoinmunes. Dentro de las causas infecciosas, destacan los virus de la familia herpes y los virus hepatotropos; sin embargo, también se ha relacionado con virus respiratorios y en concreto con el virus de la gripe, en cuyo caso, el pronóstico es bueno. Presentamos el caso de una niña de cuatro años que debutó con cuadro de fallo hepático agudo secundario a infección por virus influenza A con una evolución muy favorable.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Acute liver failure is a severe disease uncommon in children, that needs a multidisciplinar approach. In over a half of the patients the etiology is unknown. Nevertheless, remains very important for the management and prognosis to understand the main etiologies upon the group of ages. The causes may be divided in infec­tious, toxin/drug, metabolic, and autoinmune. Over the infectious etiologies the herpes virus and other hepatotropic viruses are the most frequent. However, respiratory viruses, and particularly Virus Influenza have been identified as potential cause of acute liver failure, in which the prognosis is significantly better. We report on a four-year-old girl who developed acute liver failure due to an influenza A infection with very good outcome.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Fallo hepático agudo]]></kwd>
<kwd lng="es"><![CDATA[Gripe]]></kwd>
<kwd lng="en"><![CDATA[Acute liver failure]]></kwd>
<kwd lng="en"><![CDATA[Influenza]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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