<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1699-695X</journal-id>
<journal-title><![CDATA[Revista Clínica de Medicina de Familia]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Clin Med Fam]]></abbrev-journal-title>
<issn>1699-695X</issn>
<publisher>
<publisher-name><![CDATA[Sociedad Española de Medicina de Familia y Comunitaria]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1699-695X2017000200150</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Calcifilaxis en una paciente sin insuficiencia renal avanzada]]></article-title>
<article-title xml:lang="en"><![CDATA[Calciphylaxis in a patient without advanced renal failure]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sánchez Ruiz-Granados]]></surname>
<given-names><![CDATA[Elena]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Domínguez Herrera]]></surname>
<given-names><![CDATA[Juan Manuel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Macías García]]></surname>
<given-names><![CDATA[Laura]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Complejo Hospitalario de Huelva Hospital Infanta Elena ]]></institution>
<addr-line><![CDATA[Huelva ]]></addr-line>
<country>España</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2017</year>
</pub-date>
<volume>10</volume>
<numero>2</numero>
<fpage>150</fpage>
<lpage>153</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S1699-695X2017000200150&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S1699-695X2017000200150&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S1699-695X2017000200150&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen: La calcifilaxis es una enfermedad poco frecuente, aunque presenta una elevada tasa de mortalidad debido sobre todo a complicaciones como sepsis o gangrena. Generalmente se asocia a insuficiencia renal severa y en otras ocasiones a alteraciones del metabolismo calcio-fósforo o al uso de corticoides para enfermedades autoinmunes. Se presenta como lesiones cutáneas que se pueden ulcerar o infectar, debiendo diferenciarlas de las lesiones de causa vascular mediante el estudio histológico de la biopsia de la lesión. La biopsia cutánea muestra alteraciones histológicas características que facilitan el diagnóstico diferencial de esta patología. Para su tratamiento, se deben identificar y corregir los posibles factores implicados en su aparición. El tiosulfato de sodio es útil para el tratamiento. Presentamos el caso de una paciente con insuficiencia renal leve que padeció dicha entidad con buena evolución tras tratamiento.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract: Calciphylaxis is a relatively rare disease associated with high mortality rates due to potential complications of sepsis or gangrene. It is observed mainly in patients with severe kidney disease, and in other cases it is associated with altered calcium-phosphorus metabolism or to the use of corticosteroids in the treatment of autoimmune diseases. It is characterized by painful skin lesions that may become ulcerated or infected. We must differentiate them from vascular lesions through a histological study of the lesion biopsy. The skin biopsy shows characteristic histological findings that facilitate differential diagnosis. As a treatment we must identify and correct risk factors involved in its development. Sodium thiosulphate has proved to be an effective treatment. We present the case of a patient with mild kidney disease who suffered calciphylaxis with good outcome after treatment.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Calcifilaxis]]></kwd>
<kwd lng="es"><![CDATA[Insuficiencia Renal]]></kwd>
<kwd lng="es"><![CDATA[Lesiones de la Piel]]></kwd>
<kwd lng="es"><![CDATA[Biopsia de la Piel]]></kwd>
<kwd lng="en"><![CDATA[Calciphylaxis]]></kwd>
<kwd lng="en"><![CDATA[Renal Insufficiency]]></kwd>
<kwd lng="en"><![CDATA[Skin Lesions]]></kwd>
<kwd lng="en"><![CDATA[Skin Biopsy]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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