<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1699-695X</journal-id>
<journal-title><![CDATA[Revista Clínica de Medicina de Familia]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Clin Med Fam]]></abbrev-journal-title>
<issn>1699-695X</issn>
<publisher>
<publisher-name><![CDATA[Sociedad Española de Medicina de Familia y Comunitaria]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1699-695X2019000300163</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Lengua blanca: leucoplasia verrucosa proliferativa]]></article-title>
<article-title xml:lang="en"><![CDATA[White tongue: proliferative verrucous leukoplakia]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Altozano-Rodulfo]]></surname>
<given-names><![CDATA[Paloma]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sierra-Santos]]></surname>
<given-names><![CDATA[Lucía]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Universitario Ramón y Cajal . Centro de Salud García Noblejas ]]></institution>
<addr-line><![CDATA[Madrid ]]></addr-line>
<country>España</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Consultorio Local de El Boalo  ]]></institution>
<addr-line><![CDATA[Madrid ]]></addr-line>
<country>España</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Grupo de Trabajo de Enfermedades Raras de semFYC  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2019</year>
</pub-date>
<volume>12</volume>
<numero>3</numero>
<fpage>163</fpage>
<lpage>166</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S1699-695X2019000300163&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S1699-695X2019000300163&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S1699-695X2019000300163&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN Presentamos un caso de leucoplasia verrucosa proliferativa, que es una lesión multifocal y progresiva que se presenta en forma de placas blancas en la cavidad oral, de etiología desconocida, resistente a todo intento de tratamiento y con alta recurrencia. Su conocimiento y seguimiento es de especial relevancia por la alta tasa de malignización a carcinoma de células escamosas y a carcinoma verrucoso. Es decir, se trata de una lesión premaligna agresiva, sin claro consenso sobre su etiología, y sin tratamiento efectivo en el momento actual, por lo que requiere de su conocimiento, diagnóstico precoz y seguimiento estricto.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT We present a case of proliferative verrucous leukoplakia, a multifocal progressive lesion that occurs as white patches in the oral cavity, of unknown etiology, treatment resistant, and with a high recurrence rate. Knowledge and follow-up of this disease is particularly relevant due to its high risk of progressing to malignant squamous cell carcinoma and to verrucous carcinoma. That is, it is an aggressive premalignant lesion, lacking an agreed etiology and an effective treatment at the present time. Therefore it requires knowledge of it, an early diagnosis and a close follow-up.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Leucoplasia]]></kwd>
<kwd lng="es"><![CDATA[Neoplasias de la Boca]]></kwd>
<kwd lng="es"><![CDATA[Atención Primaria de Salud]]></kwd>
<kwd lng="en"><![CDATA[Leukoplakia]]></kwd>
<kwd lng="en"><![CDATA[Mouth Neoplasms]]></kwd>
<kwd lng="en"><![CDATA[Primary Health Care]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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</article>
