<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1699-695X</journal-id>
<journal-title><![CDATA[Revista Clínica de Medicina de Familia]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Clin Med Fam]]></abbrev-journal-title>
<issn>1699-695X</issn>
<publisher>
<publisher-name><![CDATA[Sociedad Española de Medicina de Familia y Comunitaria]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1699-695X2021000100012</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Cumplimiento terapéutico en pacientes en tratamiento con anticoagulantes orales en Atención Primaria]]></article-title>
<article-title xml:lang="en"><![CDATA[Therapeutic compliance in patients being treated with oral anticoagulants in Primary Care]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[David Iglesias]]></surname>
<given-names><![CDATA[Cristina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[García Martín]]></surname>
<given-names><![CDATA[Silvia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Casas Sepúlveda]]></surname>
<given-names><![CDATA[Rosa Mª]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Martín Ballesteros]]></surname>
<given-names><![CDATA[César Pedro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Villarín Castro]]></surname>
<given-names><![CDATA[Alejandro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Zona Básica de Salud de Sonseca  ]]></institution>
<addr-line><![CDATA[Toledo ]]></addr-line>
<country>(</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Consultorio de Mocejón  ]]></institution>
<addr-line><![CDATA[Toledo ]]></addr-line>
<country>España</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Consultorio del Señorío de Illescas  ]]></institution>
<addr-line><![CDATA[Toledo ]]></addr-line>
<country>España</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Consultorio de los Olivos  ]]></institution>
<addr-line><![CDATA[Toledo ]]></addr-line>
<country>España</country>
</aff>
<aff id="Af5">
<institution><![CDATA[,Unidad Docente de Toledo  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>España</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2021</year>
</pub-date>
<volume>14</volume>
<numero>1</numero>
<fpage>12</fpage>
<lpage>17</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S1699-695X2021000100012&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S1699-695X2021000100012&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S1699-695X2021000100012&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Objetivo: evaluar y comparar el cumplimiento terapéutico entre los diferentes anticoagulantes orales.  Diseño: estudio descriptivo transversal.  Emplazamiento: Atención Primaria. Zona Básica de Salud de Bargas.  Participantes: se incluyó a pacientes que llevasen más de 6 meses en tratamiento con anticoagulantes orales, pertenecientes a seis cupos de Medicina Familiar. Se excluyó a pacientes desplazados, incapaces de tomar la medicación de forma autónoma, ingresados o fallecidos durante el estudio.  Mediciones principales: las variables estudiadas fueron: edad, sexo, nivel educativo, unidad familiar, tiempo de tratamiento, tipo de anticoagulante, efectos secundarios, polimedicación, tipo de receta, educación para la salud y cumplimiento terapéutico. Se realizó estadística descriptiva y analítica.  Resultados: se evaluaron 110 pacientes con una edad media de 73,02 (desviación estándar [DE]: 12,06) años. Un 29,1% en tratamiento con anticoagulantes orales de acción directa (ACOD). La mediana de tiempo de tratamiento fue de 47 meses (rango intercuartílico: 16-77,25), el 84,5% eran polimedicados (7,36 ± 3,96 fármacos de media). Fueron cumplidores en total el 81,81% (intervalo de confianza [IC] 95% 73,32-88,52%). El 93,75% fue cumplidor con ACOD (IC 95% 79,19-99,23%) frente al 76,92% con acenocumarol (IC 95% 66,00-85,71%) (p = 0,055). El cumplimiento en polimedicados fue del 86%, frente al 58,8% en no polimedicados (p = 0,02).  Conclusión: Nuestro estudio ha mostrado una aparente mayor adherencia terapéutica en los pacientes tratados con ACODs con respecto a los tratados con acenocumarol. La adherencia al tratamiento es mayor en los pacientes polimedicados.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Aim: To evaluate and compare treatment compliance among different oral anticoagulants.  Design: Transversal descriptive study.  Location: Primary Care. Bargas Basic Healthcare Area.  Participants: Patients in treatment with oral anticoagulants more than 6 months who belonged to six Family Medicine quotas were included. Displaced patients, those unable to take medication autonomously, admitted to hospital or who died during the study were excluded.  Primary endpoints: The variables studied were: age, sex, educational level, family unit, treatment time, type of anticoagulant, side effects, polymedication, type of prescription, education for health and treatment compliance. Descriptive statistics and analysis were performed.  Results: 110 patients with a mean age of 73.02 (SD: 12.06) years old were studied. A total of 29.1% were in treatment with oral anticoagulants (OACs). Median treatment time was 47 months (interquartile range: 16-77.25). A total of 84.5% were polymedicated (7.36±3.96 drugs on average). In total 81.81% (95%CI 73.32-88.52%) were compliant. A total of 93.75% complied with OACs (95%CI 79.19-99.23%) compared to 76.92% with acenocumarol (95%CI 66.00-85.71%) (p=0.055). Compliance in polymedicated patients was 86% compared to 58.8% in non-polymedicated patients (p=0.02).  Conclusion: Our study revealed an apparent greater treatment adherence in patients treated with OACs in regard to those treated with acenocumarol. Treatment adherence is greater in polymedicated patients.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Cumplimiento y Adherencia al Tratamiento]]></kwd>
<kwd lng="es"><![CDATA[Atención Primaria de Salud]]></kwd>
<kwd lng="es"><![CDATA[Anticoagulantes]]></kwd>
<kwd lng="en"><![CDATA[Anticoagulants]]></kwd>
<kwd lng="en"><![CDATA[Primary Health Care]]></kwd>
<kwd lng="en"><![CDATA[Treatment Adherence and Compliance]]></kwd>
</kwd-group>
</article-meta>
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