<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1886-5887</journal-id>
<journal-title><![CDATA[Revista de Bioética y Derecho]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Bioética y Derecho]]></abbrev-journal-title>
<issn>1886-5887</issn>
<publisher>
<publisher-name><![CDATA[Observatori de Bioètica i Dret - Cátedra UNESCO de Bioética]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1886-58872019000300004</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[La mejora genética humana en los tiempos del CRISPR/Cas9]]></article-title>
<article-title xml:lang="en"><![CDATA[Human genetic enhancement in times of CRISPR/Cas9]]></article-title>
<article-title xml:lang="ca"><![CDATA[La millora genètica humana en els temps del CRISPR/Cas9]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Santaló]]></surname>
<given-names><![CDATA[Josep]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universitat Autònoma de Barcelona Facultad de Biociencias Departamento de Biología Celular, Fisiología e Inmunología]]></institution>
<addr-line><![CDATA[Bellaterra ]]></addr-line>
<country>España</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2019</year>
</pub-date>
<numero>47</numero>
<fpage>33</fpage>
<lpage>41</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S1886-58872019000300004&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S1886-58872019000300004&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S1886-58872019000300004&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen La mejora genética en la especie humana ha suscitado desde siempre un amplio debate por lo que respecta a los aspectos éticos asociados a ella. Dicho debate había quedado circunscrito al ámbito meramente especulativo hasta la aparición de una nueva tecnología de edición genómica (CRISPR/Cas9) la cual lo ha reabierto al vislumbrarse una aplicabilidad a medio plazo que nos obliga a retomarlo y a reflexionar sobre la conveniencia o no de iniciar un camino excepcional en la historia de la evolución humana. En este artículo se detallan algunos de los argumentos esgrimidos a favor y en contra referentes a esta tecnología.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Human genetic enhancement has always risen a wide debate regarding the ethical aspects associated with it. This debate had remained into a merely speculative realm until the appearance of a new genome editing technology (CRISPR / Cas9) which has reopened it when a mid-term applicability can be envisaged. This new situation forces us to resume it and ponder the convenience or not of initiating an exceptional path in the history of human evolution. This article details some of the arguments put forward in favour and against this technology.]]></p></abstract>
<abstract abstract-type="short" xml:lang="ca"><p><![CDATA[Resum La millora genètica en l'espècie humana ha suscitat des de sempre un ampli debat pel que respecta als aspectes ètics associats a ella. Aquest debat havia quedat circumscrit a l'àmbit merament especulatiu fins l'aparició d'una nova tecnologia d'edició genòmica (CRISPR/Cas9) la qual l'ha reobert en albirar-se una aplicabilitat a mitjà termini que ens obliga a reflexionar sobre la conveniència o no d'iniciar un camí excepcional en la història de l'evolució humana. En aquest article es detallen alguns dels arguments esgrimits a favor i en contra referents a aquesta tecnologia.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[edición genómica]]></kwd>
<kwd lng="es"><![CDATA[mejora genética humana]]></kwd>
<kwd lng="es"><![CDATA[mejora biológica humana]]></kwd>
<kwd lng="es"><![CDATA[modificación genética humana]]></kwd>
<kwd lng="es"><![CDATA[edición genética]]></kwd>
<kwd lng="en"><![CDATA[genomic editing]]></kwd>
<kwd lng="en"><![CDATA[human genetic improvement]]></kwd>
<kwd lng="en"><![CDATA[human biological improvement]]></kwd>
<kwd lng="en"><![CDATA[human genetic modification]]></kwd>
<kwd lng="en"><![CDATA[genetic editing]]></kwd>
<kwd lng="ca"><![CDATA[edició genòmica]]></kwd>
<kwd lng="ca"><![CDATA[millora genètica humana]]></kwd>
<kwd lng="ca"><![CDATA[millora biològica humana]]></kwd>
<kwd lng="ca"><![CDATA[modificació genètica humana]]></kwd>
<kwd lng="ca"><![CDATA[edició genètica]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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