<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1886-5887</journal-id>
<journal-title><![CDATA[Revista de Bioética y Derecho]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Bioética y Derecho]]></abbrev-journal-title>
<issn>1886-5887</issn>
<publisher>
<publisher-name><![CDATA[Observatori de Bioètica i Dret - Cátedra UNESCO de Bioética]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1886-58872020000200006</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[La protección de la diversidad en el patrimonio genético: implicaciones bioéticas y jurídicas en el uso de CRISPR-Cas9 como herramienta de edición genómica en humanos]]></article-title>
<article-title xml:lang="en"><![CDATA[The preservation of diversity in genetic heritage: bioethical and legal implications of the use of CRISPR-Cas9 as a gene editing tool in human beings]]></article-title>
<article-title xml:lang="ca"><![CDATA[La protecció de la diversitat en el patrimoni genètic: implicacions bioètiques i jurídiques en l'ús de CRISPR-Cas9 com a eina d'edició genòmica en humans]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Dantas]]></surname>
<given-names><![CDATA[Carlos Henrique Félix]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ferraz]]></surname>
<given-names><![CDATA[Carolina Valença]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Falcão]]></surname>
<given-names><![CDATA[Juliana Rocha de Morales]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidade Federal de Pernambuco  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Brazil</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Católica de Pernambuco  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Brasil</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Memorial University of Newfoundland  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Canada</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2020</year>
</pub-date>
<numero>49</numero>
<fpage>77</fpage>
<lpage>91</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S1886-58872020000200006&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S1886-58872020000200006&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S1886-58872020000200006&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen El objetivo de este artículo es comprender cómo el CRISPR-Cas9 puede funcionar como una tecnología viable en la construcción del proyecto de parentalidad para promover el ejercicio de la libertad en el proceso de autonomía reproductiva. Sin embargo, a pesar de la posibilidad del uso en la línea germinal humana, se intentó investigar los límites y el alcance de esta percepción de libertad. Así, a través del uso de investigaciones documentales y bibliográficas, se buscaron datos sobre la viabilidad de la preservación del patrimonio genético como expresión de la diversidad en la humanidad. De esta forma, se percibió que es necesario superar pensamientos higienistas de limpiar "defectos", considerando que toda vida es digna de ser vivida.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract The scope of this paper was to understand how CRISPR-Cas9 can function as a viable technology in the construction of the parenting project in order to promote freedom in the process of procreative autonomy. However, regarding the possibility of its use to cause genetic manipulation in the human germline, we sought to ascertain the limits and scope of this perception of freedom. Thus, through the use of documentary and bibliographical method, data about the viability of the preservation of the genetic patrimony as an expression of the diversity in humanity was researched. Therefore, it was perceived as necessary to overcome the hygienist thoughts of cleaning up "defects", considering all life as worthy of being lived.]]></p></abstract>
<abstract abstract-type="short" xml:lang="ca"><p><![CDATA[Resum L'objectiu del article era comprendre com CRISPR-CAS9 pot funcionar com una tecnologia viable en la construcció del projecte de parentalitat per promoure l'exercici de la llibertat en el procés d'autonomia reproductiva. No obstant això, tot i la possibilitat del seu ús en la línia germinal humana, es van intentar investigar els límits i l'abast d'aquesta percepció de llibertat. Així, a través de l'ús d'investigacions documentals i bibliogràfiques, es van buscar dades sobre la viabilitat de la preservació del patrimoni genètic com a expressió de la diversitat a la humanitat. D'aquesta manera, es va percebre que cal superar pensaments higienistes de netejar "defectes", considerant que tota vida és digna de ser viscuda.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[autonomía privada]]></kwd>
<kwd lng="es"><![CDATA[construcción del proyecto parental]]></kwd>
<kwd lng="es"><![CDATA[edición de genes]]></kwd>
<kwd lng="es"><![CDATA[patrimonio genético]]></kwd>
<kwd lng="es"><![CDATA[derecho a la diferencia]]></kwd>
<kwd lng="en"><![CDATA[autonomy]]></kwd>
<kwd lng="en"><![CDATA[parental project]]></kwd>
<kwd lng="en"><![CDATA[gene editing]]></kwd>
<kwd lng="en"><![CDATA[genetic inheritance]]></kwd>
<kwd lng="en"><![CDATA[the right to difference]]></kwd>
<kwd lng="ca"><![CDATA[autonomia privada]]></kwd>
<kwd lng="ca"><![CDATA[construcció del projecte parental]]></kwd>
<kwd lng="ca"><![CDATA[edició de genes]]></kwd>
<kwd lng="ca"><![CDATA[patrimoni genètic]]></kwd>
<kwd lng="ca"><![CDATA[dret a la diferència]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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