<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1886-5887</journal-id>
<journal-title><![CDATA[Revista de Bioética y Derecho]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Bioética y Derecho]]></abbrev-journal-title>
<issn>1886-5887</issn>
<publisher>
<publisher-name><![CDATA[Observatori de Bioètica i Dret - Cátedra UNESCO de Bioética]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1886-58872021000300007</article-id>
<article-id pub-id-type="doi">10.1344/rbd2021.53.34049</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[La terapia génica en México y España, una aproximación bioética desde la investigación científica]]></article-title>
<article-title xml:lang="en"><![CDATA[Gene therapy in Mexico and Spain, a bioethical approach from scientific research]]></article-title>
<article-title xml:lang="ca"><![CDATA[La teràpia gènica a Mèxic i Espanya, una aproximació bioètica des de la recerca científica]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Olivo-Yepez]]></surname>
<given-names><![CDATA[Álvaro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Linares-Márquez]]></surname>
<given-names><![CDATA[Pascual]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Delgado-Enciso]]></surname>
<given-names><![CDATA[Iván]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
<xref ref-type="aff" rid="Ab"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Morales-Romero]]></surname>
<given-names><![CDATA[Zoylo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Veracruzana Facultad de Biología ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Veracruzana Facultad de Biología ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad de Colima  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>México</country>
</aff>
<aff id="A3b">
<institution><![CDATA[,Instituto Estatal de Cancerología  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Universidad Veracruzana Facultad de Estadística e Informática ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>México</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2021</year>
</pub-date>
<numero>53</numero>
<fpage>117</fpage>
<lpage>138</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S1886-58872021000300007&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S1886-58872021000300007&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S1886-58872021000300007&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen La terapia génica es una línea de investigación que, por medio de la transferencia genética, busca nuevos tratamientos a enfermedades que son difíciles de tratar mediante métodos tradicionales. Esta línea de investigación tiene características específicas para realizarse, como los métodos de transferencia genética y las enfermedades a tratar. No obstante, las características de la terapia génica pueden estar influenciadas por el entorno social, económico y/o político del país donde se realiza, para que la investigación tenga un objetivo y/o aplicación específica. México y España son países que tienen proyectos de terapia génica en sus instituciones educativas y de salud. Sin embargo, se desconocen las características que dicha línea tiene en los países mencionados y la influencia que el contexto de cada país ejerce en la terapia génica. En el presente estudio se realizó un esfuerzo por identificar las características que la investigación de terapia génica tiene en México y España por medio de la aplicación de cuestionarios dirigidos a investigadores de ambos países. Se utilizaron tablas de frecuencias para identificar las características generales de la terapia génica de ambos países. Así como, un análisis correlacional para identificar, entre todas las respuestas obtenidas, las características distintivas de cada país. Los resultados sugieren que la influencia del contexto español presenta las características necesarias para llevar a la terapia génica a una etapa clínica, mientras que el contexto mexicano se limita la promoción de la investigación básica de esta línea de investigación.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Gene therapy is a research line that; seeks new treatments for diseases that are difficult to treat by traditional methods. This line of research has specific characteristics to be carried out, such as genetic transfer methods and diseases to treat. However, the characteristics of gene therapy may be influenced by social, economic and/or political environment of the country where it is performed, therefore the research might have a specific objective and/or application. Mexico and Spain are countries that have gene therapy projects in their educational and health institutions. However, the characteristics of this line in the above-mentioned countries and the influence that the context of each country has on gene therapy are unknown. This article aims to identify the characteristics that gene therapy research has in Mexico and Spain, through the application of questionnaires addressed to researchers from both countries. Frequency tables were used to identify the general characteristics of gene therapy in Mexico and Spain, as well as a correlational analysis to identify, among all the responses obtained, the distinctive characteristics of each country. The results suggest that the influence of the Spanish context allows the necessary characteristics to bring gene therapy to a clinical stage, while the Mexican context is restricted to promoting the basic research of this line of research.]]></p></abstract>
<abstract abstract-type="short" xml:lang="ca"><p><![CDATA[Resum La teràpia gènica és una línia de recerca que, per mitjà de la transferència genètica, cerca nous tractaments a malalties que són difícils de tractar mitjançant mètodes tradicionals. Aquesta línia de recerca té característiques específiques per a realitzar-se, com els mètodes de transferència genètica i les malalties a tractar. No obstant això, les característiques de la teràpia gènica poden estar influenciades per l'entorn social, econòmic i/o polític del país on es realitza, perquè la recerca tingui un objectiu i/o aplicació específica. Mèxic i Espanya són països que tenen projectes de teràpia gènica en les seves institucions educatives i de salut. No obstant això, es desconeixen les característiques que aquesta línia té als països esmentats i la influència que el context de cada país exerceix en la teràpia gènica. En el present estudi es va realitzar un esforç per identificar les característiques que la recerca de teràpia gènica té a Mèxic i Espanya, per mitjà de l'aplicació de qüestionaris dirigits a investigadors de tots dos països. Es van utilitzar taules de freqüències per a identificar les característiques generals de la teràpia gènica de tots dos països, així com una anàlisi correlacional per a identificar, entre totes les respostes obtingudes, les característiques distintives de cada país. Els resultats suggereixen que la influència del context espanyol presenta les característiques necessàries per a portar a la teràpia gènica a una etapa clínica, mentre que el context mexicà es limita la promoció de la recerca bàsica d'aquesta línia de recerca.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Bioética]]></kwd>
<kwd lng="es"><![CDATA[Terapia génica: Investigación]]></kwd>
<kwd lng="es"><![CDATA[España]]></kwd>
<kwd lng="es"><![CDATA[México]]></kwd>
<kwd lng="en"><![CDATA[Bioethical]]></kwd>
<kwd lng="en"><![CDATA[Gene therapy]]></kwd>
<kwd lng="en"><![CDATA[Research]]></kwd>
<kwd lng="en"><![CDATA[Spain]]></kwd>
<kwd lng="en"><![CDATA[Mexico]]></kwd>
<kwd lng="ca"><![CDATA[Bioètica]]></kwd>
<kwd lng="ca"><![CDATA[Teràpia gènica: Recerca]]></kwd>
<kwd lng="ca"><![CDATA[Espanya]]></kwd>
<kwd lng="ca"><![CDATA[Mèxic]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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