<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1886-5887</journal-id>
<journal-title><![CDATA[Revista de Bioética y Derecho]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Bioética y Derecho]]></abbrev-journal-title>
<issn>1886-5887</issn>
<publisher>
<publisher-name><![CDATA[Observatori de Bioètica i Dret - Cátedra UNESCO de Bioética]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1886-58872021000300011</article-id>
<article-id pub-id-type="doi">10.1344/rbd2021.53.33505</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Ethical issues related to gen editing using CRISPR-Cas9 technology]]></article-title>
<article-title xml:lang="es"><![CDATA[Cuestiones éticas de la edición genética mediante la tecnología CRISPR-Cas9]]></article-title>
<article-title xml:lang="ca"><![CDATA[Qüestions ètiques de l'edició genètica mitjançant la tecnología CRISPR-Cas9]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Actis]]></surname>
<given-names><![CDATA[Andrea Mariel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Buenos Aires Facultad de Medicina Departamento de Humanidades Médicas]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Argentina</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2021</year>
</pub-date>
<numero>53</numero>
<fpage>203</fpage>
<lpage>214</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S1886-58872021000300011&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S1886-58872021000300011&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S1886-58872021000300011&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Immersed already in the 4th industrial revolution, clearly the digital age has invaded our lives. People tend to celebrate every technological and scientific advance without thinking properly about the possible undesired side effects or unexpected consequences. One of the most outstanding achievements of the last years has been the CRISPR/Cas9 technique. It seems to be the magic wand to solve whatever. In this article I propose to think critically about the ethical issues related to this incredible technique. I will focus this work on 3 ethical aspects of gene editing: 1. The link between gene editing and the old concept of eugenics; 2. Aspects related to the idea of modifying human genetics in order to conquer other planets and 3. The ethical implications of uploading all these data to the web. Finally, I suggest focusing on interdisciplinary ethical discussion, the dialogue between professionals, institutions and government which must ensure the protection of the autonomy of patients and the safeguarding of their rights. To conclude, the suggestion of considering the role of Universities in ethical education of the future professionals with a practical rather than a theoretical approach is considered, with special attention to the integration of cybernetics in medicine.]]></p></abstract>
<abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen Inmersos ya en la 4ª revolución industrial, claramente la era digital ha invadido nuestras vidas. La gente tiende a celebrar cada avance tecnológico y científico sin pensar adecuadamente en los posibles efectos secundarios no deseados o las consecuencias inesperadas. Uno de los logros más destacados de los últimos años ha sido la técnica CRISPR/Cas9. Parece ser la varita mágica para resolver lo que sea. En este artículo me propongo pensar críticamente sobre las cuestiones éticas relacionadas con esta increíble técnica. Centraré este trabajo en 3 aspectos éticos de la edición de genes: 1. El vínculo entre la edición de genes y el antiguo concepto de eugenesia; 2. Aspectos relacionados con la idea de modificar la genética humana para conquistar otros planetas y 3. Las implicancias éticas de subir todos estos datos a la web. Finalmente, sugiero enfocarse en la discusión ética interdisciplinaria, el diálogo entre profesionales, instituciones y gobierno que debe asegurar la protección de la autonomía de los pacientes y la salvaguarda de sus derechos. Para concluir, se plantea la sugerencia de considerar el papel de las Universidades en la educación ética de los futuros profesionales con un enfoque más práctico que teórico, con especial atención a la integración de la cibernética en la medicina.]]></p></abstract>
<abstract abstract-type="short" xml:lang="ca"><p><![CDATA[Resum Immersos ja en la 4a revolució industrial, clarament l'era digital ha envaït les nostres vides. La gent tendeix a celebrar cada avanç tecnològic i científic sense pensar adequadament en els possibles efectes secundaris no desitjats o les conseqüències inesperades. Un dels assoliments més destacats dels últims anys ha estat la tècnica CRISPR/*Cas9. Sembla ser la vareta màgica per a resoldre el que sigui. En aquest article em proposo pensar críticament sobre les qüestions ètiques relacionades amb aquesta increïble tècnica. Centraré aquest treball en 3 aspectes ètics de l'edició de gens: 1. El vincle entre l'edició de gens i l'antic concepte d'eugenèsia; 2. Aspectes relacionats amb la idea de modificar la genètica humana per a conquistar altres planetes i 3. Les implicancias ètiques de pujar totes aquestes dades a la web. Finalment, suggereixo enfocar-se en la discussió ètica interdisciplinària, el diàleg entre professionals, institucions i govern que ha d'assegurar la protecció de l'autonomia dels pacients i la salvaguarda dels seus drets. Per a concloure, es planteja el suggeriment de considerar el paper de les Universitats en l'educació ètica dels futurs professionals amb un enfocament més pràctic que teòric, amb especial atenció a la integració de la cibernètica en la medicina.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[CRISPR/Cas9]]></kwd>
<kwd lng="en"><![CDATA[Bioethics, Eugenics]]></kwd>
<kwd lng="en"><![CDATA[Mars mission]]></kwd>
<kwd lng="en"><![CDATA[Big data]]></kwd>
<kwd lng="en"><![CDATA[Human enhancement]]></kwd>
<kwd lng="en"><![CDATA[Gene Editing]]></kwd>
<kwd lng="es"><![CDATA[CRISPR/Cas9]]></kwd>
<kwd lng="es"><![CDATA[Bioética]]></kwd>
<kwd lng="es"><![CDATA[Eugenesia]]></kwd>
<kwd lng="es"><![CDATA[Misión a Marte]]></kwd>
<kwd lng="es"><![CDATA[Big Data]]></kwd>
<kwd lng="es"><![CDATA[Mejora Humana]]></kwd>
<kwd lng="es"><![CDATA[Edición genética]]></kwd>
<kwd lng="ca"><![CDATA[CRISPR/Cas9, Bioètica]]></kwd>
<kwd lng="ca"><![CDATA[Eugenèsia]]></kwd>
<kwd lng="ca"><![CDATA[Missió a Mart]]></kwd>
<kwd lng="ca"><![CDATA[Big Data]]></kwd>
<kwd lng="ca"><![CDATA[Millora Humana]]></kwd>
<kwd lng="ca"><![CDATA[Edició genètica]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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