<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2254-2884</journal-id>
<journal-title><![CDATA[Enfermería Nefrológica]]></journal-title>
<abbrev-journal-title><![CDATA[Enferm Nefrol]]></abbrev-journal-title>
<issn>2254-2884</issn>
<publisher>
<publisher-name><![CDATA[Sociedad Española de Enfermería Nefrológica]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2254-28842017000300259</article-id>
<article-id pub-id-type="doi">10.4321/s2254-28842017000300010</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Perfil sintomático de los pacientes con Enfermedad Renal Crónica Estadio 4 y 5]]></article-title>
<article-title xml:lang="en"><![CDATA[Symptomatic profile of patients with Chronic Kidney Disease Stage 4 and 5]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gutiérrez Sánchez]]></surname>
<given-names><![CDATA[Daniel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Leiva-Santos]]></surname>
<given-names><![CDATA[Juan P.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Macías López]]></surname>
<given-names><![CDATA[María José]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Cuesta Vargas]]></surname>
<given-names><![CDATA[Antonio I.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Fundación Cudeca  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Spain</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital de Manacor  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Spain</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital Regional Universitario de Málaga Servicio de Nefrología ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Spain</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Universidad de Málaga Instituto de Investigación Biomédico de Málaga (IBIMA) Departamento de Fisioterapia]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Spain</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>09</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>09</month>
<year>2017</year>
</pub-date>
<volume>20</volume>
<numero>3</numero>
<fpage>259</fpage>
<lpage>266</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S2254-28842017000300259&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S2254-28842017000300259&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S2254-28842017000300259&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  Introducción: Los pacientes con Enfermedad Renal Crónica Avanzada (ERCA) experimentan una gran variedad de síntomas que afectan negativamente la calidad de vida del paciente.  Objetivos: Determinar la prevalencia e intensidad de síntomas y analizar su asociación con el filtrado glomerular (FG) y la comorbilidad.  Material y Método: Estudio transversal en el que se describe la sintomatología del paciente con ERCA en diálisis y prediálisis y se realiza un análisis de la asociación de los síntomas con el FG y la comorbilidad. Para la evaluación de síntomas se utilizó la versión española modificada de la Palliative care Outcome Scale-Symptoms Renal (POS-S Renal), un cuestionario validado para evaluar la sintomatología en esta población. La comorbilidad fue evaluada con el índice de comorbilidad de Charlson modificado (ICCm).  Resultados: 180 pacientes con ERCA fueron incluidos en este estudio. Más del 44% de pacientes describieron debilidad, dolor, depresión y dificultad para dormir. Se encontraron diferencias significativas en ambos grupos para síntomas como la debilidad (p=0.027), poca movilidad (p=0.018), somnolencia (p=0.03), estreñimiento (p=0.015) y piernas inquietas (p&lt;0.01). El declive de la función renal se asoció con la sintomatología (p=0,04). No encontramos asociación entre la comorbilidad y la sintomatología (p=0,15).  Conclusiones: Los pacientes con ERCA sufren una elevada carga de síntomas. La evaluación y monitorización sistemática de síntomas mediante herramientas como el POS-S Renal puede ser útil en el ámbito clínico y en investigación. La integración de los Cuidados Paliativos en los Servicios de Nefrología puede contribuir a la optimización del manejo sintomático en esta población.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Introduction: Patients with Advanced Chronic Kidney Disease (ACKD) experience multiple symptoms that negatively affect the quality of life.  Aims: To determine the prevalence and severity of symptoms, and their association with the glomerular filtration rate (GFR) and comorbidities.  Material and method: A cross-sectional study to examine the prevalence of symptoms in patients with ACKD on dialysis and predialysis, and their association with GFR and comorbidities was carried out. Symptom data were collected using the Spanish modified version of Palliative care Outcome Scale- Symptoms Renal (POS-S Renal), a validated questionnaire to assess symptoms in this population. Comorbidity was collected and scored according to the modified Charlson Comorbidity Index (mCCI).  Results: The study sample included 180 patients with ACKD. More than 44% of patients described weakness, pain, depression and difficulty sleeping. There was a significant difference in the prevalence of symptoms between groups for weakness (p=0.027), poor mobility (p=0.018), drowsiness (p=0.03), constipation (p=0.015) and restless legs (p&lt;0.01). There was no association between disease severity and symptoms (p=0,04). There was no significant correlation between comorbidities and symptoms (p=0,15).  Conclusions: Patients with ACKD experience a high level of symptom burden. Routine symptom assessment using tools such as the POS-S Renal can be useful in clinical and research settings. Integrating the principles of Palliative Care in Nephrology Services can be beneficial for optimizing the symptom management in this population.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[enfermedad renal crónica avanzada]]></kwd>
<kwd lng="es"><![CDATA[evaluación de síntomas]]></kwd>
<kwd lng="es"><![CDATA[cuestionarios]]></kwd>
<kwd lng="en"><![CDATA[advanced chronic kidney disease]]></kwd>
<kwd lng="en"><![CDATA[symptoms assessment]]></kwd>
<kwd lng="en"><![CDATA[questionnaires]]></kwd>
</kwd-group>
</article-meta>
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