<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2340-9894</journal-id>
<journal-title><![CDATA[Ars Pharmaceutica (Internet)]]></journal-title>
<abbrev-journal-title><![CDATA[Ars Pharm]]></abbrev-journal-title>
<issn>2340-9894</issn>
<publisher>
<publisher-name><![CDATA[Universidad de Granada]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2340-98942017000100005</article-id>
<article-id pub-id-type="doi">10.30827/ars.v58i1.5919</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Isoflavonoids from the rhizomes of Iris hungarica and antibacterial activity of the dry rhizomes extract]]></article-title>
<article-title xml:lang="es"><![CDATA[Isoflavonoides de los rizomas de Iris hungarica y actividad antibacteriana del extracto de rizomas seco]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mykhailenko]]></surname>
<given-names><![CDATA[Olga]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Kovalyov]]></surname>
<given-names><![CDATA[Volodumur]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Kovalyov]]></surname>
<given-names><![CDATA[Sergiy]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Krechun]]></surname>
<given-names><![CDATA[Anastasiia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,National University of Pharmacy Department of Botany ]]></institution>
<addr-line><![CDATA[Kharkiv ]]></addr-line>
<country>Ukraine</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,National University of Pharmacy Department of Pharmacognosy ]]></institution>
<addr-line><![CDATA[Kharkiv ]]></addr-line>
<country>Ukraine</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,National University of Pharmacy Department of nutritiology and pharmaceutical bromatology ]]></institution>
<addr-line><![CDATA[Kharkiv ]]></addr-line>
<country>Ukraine</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2017</year>
</pub-date>
<volume>58</volume>
<numero>1</numero>
<fpage>39</fpage>
<lpage>45</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S2340-98942017000100005&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S2340-98942017000100005&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S2340-98942017000100005&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Aim: The aim of the work was isolation and identification of the phenolic compounds from the rhizomes of Iris hungarica.  Materials and methods: To establish by chemical and spectral methods for the structures of phenolic compounds, which were isolated from the rhizomes of Iris hungarica Waldst. et Kit. (Iridaceae family). Compounds were obtained by column chromatography on silica gel and their structures were determined by UV, IR, MS, 1H-NMR spectra methods. Preliminary screening of antibacterial activity was determined.  Results: From the ethanolic extract of the rhizomes of I. hungarica, which is widespread in Ukraine, for the first time two new for this species isoflavones, tectorigenin and tectoridin and xanthone mangiferin, together with known isoflavonoids daidzein, genistein, formononetin were isolated. The dry extract of the rhizomes of I. hungarica at a concentration of 1% has shown the highest inhibitory activity for Gram-positive bacteria and fungi.]]></p></abstract>
<abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  Objetivo: El objetivo del trabajo es el aislamiento y la identificación de los compuestos fenólicos de los rizomas de Iris hungarica.  Materiales y métodos: Se utilizaron métodos químicos y espectrales para conocer las estructuras de compuestos fenólicos que se aislaron de los rizomas de Iris hungarica Waldst. et Kit. (Familia de Iridaceae). Los compuestos se obtuvieron mediante cromatografia en columna sobre gel de sílice y se determinaron sus estructuras mediante análisis de sus espectros por UV, IR, MS, 1H-RMN. Se determinó el cribado preliminar de la actividad antibacteriana.  Resultados: Se aislaron por primera vez de los rizomas de Iris hungarica (común en Ucra-nia) dos isoflavonas, tectorigenina y tectoridina (nuevas para esta especie), el xan-tonoide mangiferina y los isoflavonoides daidzeina, genisteina y formononetina. El extracto seco de los rizomas de I. hungarica a una concentración de 1% ha mostrado la actividad inhibitoria más alta para bacterias y hongos Gram-positivos.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[isoflavonoids]]></kwd>
<kwd lng="en"><![CDATA[tectorigenin]]></kwd>
<kwd lng="en"><![CDATA[tectoridin]]></kwd>
<kwd lng="en"><![CDATA[mangiferin]]></kwd>
<kwd lng="en"><![CDATA[Iris hungarica]]></kwd>
<kwd lng="en"><![CDATA[antibacterial activity]]></kwd>
<kwd lng="es"><![CDATA[isoflavonoides]]></kwd>
<kwd lng="es"><![CDATA[tectorigenina]]></kwd>
<kwd lng="es"><![CDATA[tectoridina]]></kwd>
<kwd lng="es"><![CDATA[mangiferina]]></kwd>
<kwd lng="es"><![CDATA[Iris hungarica]]></kwd>
<kwd lng="es"><![CDATA[actividad antibacteriana]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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