<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2340-9894</journal-id>
<journal-title><![CDATA[Ars Pharmaceutica (Internet)]]></journal-title>
<abbrev-journal-title><![CDATA[Ars Pharm]]></abbrev-journal-title>
<issn>2340-9894</issn>
<publisher>
<publisher-name><![CDATA[Universidad de Granada]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2340-98942018000200001</article-id>
<article-id pub-id-type="doi">10.30827/ars.v59i2.7513</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Glycyrrhizic acid: extraction, screening and evaluation of anti&#8211;inflammatory property]]></article-title>
<article-title xml:lang="es"><![CDATA[Ácido glicirrícico: extracción, cribado y evaluación de la propiedad anti-inflamatoria]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Chauhan]]></surname>
<given-names><![CDATA[Swati]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gulati]]></surname>
<given-names><![CDATA[Neha]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Nagaich]]></surname>
<given-names><![CDATA[Upendra]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Amity University Amity Institute of Pharmacy Department of Pharmaceutics]]></institution>
<addr-line><![CDATA[Noida Uttar Pradesh]]></addr-line>
<country>India</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2018</year>
</pub-date>
<volume>59</volume>
<numero>2</numero>
<fpage>61</fpage>
<lpage>67</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S2340-98942018000200001&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S2340-98942018000200001&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S2340-98942018000200001&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[ Objective:  Glycyrrhizic acid is a widely used medicinal component as an anti-inflammatory agent, anti ulcer agent, anti-allergy agent and anti-psoriatic agent. The present investigation deals with the extraction of glycyrrhizic acid from licorice roots and evaluating its in-vitro anti inflammatory activity.  Methods:  Glycyrrhizic acid was extracted using the procedure of maceration. The extract was evaluated for its physicochemical property, biochemical tests and phytochemical properties. The Ii vitro anti- inflammatory activity was evaluated by albumin denaturation technique  Results: The results showed that the ash value and the extractive values for the extract were found to be in the limit as given by Ayurvedic Pharmacopoeia of India. Presence of flavonoids, saponins and triterpinoids were identified in the extract from phytochemical parameters. Thin layer chromatographic technique showed a retention value of 0.5 cm. The percentage inhibition showed that the extract is having some potential of healing inflammation.  Conclusion: Glycyrrhizic acid was successfully extracted from licorice roots. The evaluation parameters showed the presence of less impurity in the extract, with the potential of having anti-inflammatory property.]]></p></abstract>
<abstract abstract-type="short" xml:lang="es"><p><![CDATA[ Objetivo:  El ácido glicirrícico es un componente medicinal ampliamente utilizado como agente antiinflamatorio, agente antiulceroso, agente antialérgico y agente anti-psoriásico. La presente investigación trata de la extracción de ácido glicirrícico a partir de raíces de regaliz y la evaluación de su actividad antiinflamatoria in vitro .  Métodos:  el ácido glicirrícico fue extraído usando el procedimiento de la maceración. El extracto fue evaluado por su propiedad fisicoquímica, pruebas bioquímicas y propiedades fitoquímicas. La actividad antiinflamatoria in vitro fue evaluada por la técnica de desnaturalización de albúmina  Resultados: los resultados demostraron que el valor de la ceniza y los valores extractivos para el extracto se encontraron en el valor límite según lo dado por la farmacopea de Ayurveda de la India. La presencia de flavonoides, de saponinas y de triterpenoides fue identificada en el extracto mediante parámetros fitoquímico. La técnica cromatográfica en capa delgada demostró un valor de retención de 0,5 centímetros. La inhibición porcentual mostró que el extracto tiene algún potencial de curación de la inflamación.  Conclusión: el ácido glicirrícico fue extraído con éxito de las raíces de regaliz. Los parámetros de evaluación mostraron la presencia de menos impureza en el extracto, con el potencial de tener propiedades antiinflamatorias.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Glycyrrhizic acid]]></kwd>
<kwd lng="en"><![CDATA[Licorice roots]]></kwd>
<kwd lng="en"><![CDATA[Anti-inflammatory activity]]></kwd>
<kwd lng="en"><![CDATA[Albumin denaturation technique]]></kwd>
<kwd lng="es"><![CDATA[ácido glicirrícico]]></kwd>
<kwd lng="es"><![CDATA[raíces de regaliz]]></kwd>
<kwd lng="es"><![CDATA[actividad antiinflamatoria]]></kwd>
<kwd lng="es"><![CDATA[técnica de desnaturalización de la albúmina]]></kwd>
</kwd-group>
</article-meta>
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