<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2340-9894</journal-id>
<journal-title><![CDATA[Ars Pharmaceutica (Internet)]]></journal-title>
<abbrev-journal-title><![CDATA[Ars Pharm]]></abbrev-journal-title>
<issn>2340-9894</issn>
<publisher>
<publisher-name><![CDATA[Universidad de Granada]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2340-98942022000300003</article-id>
<article-id pub-id-type="doi">10.30827/ars.v63i3.24409</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Macrogol: evaluación de la percepción de efectividad y calidad de vida en individuos con estreñimiento]]></article-title>
<article-title xml:lang="en"><![CDATA[Macrogol: evaluation of the perception of effectiveness and quality of life in individuals with constipation]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Correia]]></surname>
<given-names><![CDATA[Nuno]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Guarner]]></surname>
<given-names><![CDATA[Francisco]]></given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Logusso]]></surname>
<given-names><![CDATA[Georgina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Sanofi  ]]></institution>
<addr-line><![CDATA[Lisboa ]]></addr-line>
<country>Portugal</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Sanofi  ]]></institution>
<addr-line><![CDATA[Barcelona ]]></addr-line>
<country>Spain</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>09</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>09</month>
<year>2022</year>
</pub-date>
<volume>63</volume>
<numero>3</numero>
<fpage>234</fpage>
<lpage>243</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S2340-98942022000300003&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S2340-98942022000300003&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S2340-98942022000300003&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  Introducción: El estreñimiento tiene una prevalencia del 14-30% en España, su causa es multifactorial y afecta negativamente al bienestar y a la calidad de vida de las personas. Entre los tratamientos para el estreñimiento funcional se encuentran los laxantes osmóticos como Macrogol 4000. El grado de satisfacción con los laxantes es proporcional a la efectividad y mejora de la calidad de vida percibidas.  Método: se realizó una encuesta en farmacias españolas a 100 consumidores que adquirían Macrogol 4000 como producto sanitario, con objeto de tratar los síntomas del estreñimiento. Se midieron los cambios en la calidad de vida y la percepción subjetiva de la efectividad a los 4, 8 y 14 días de tratamiento empleando la metodología CATI, basada en encuestas telefónicas.  Resultados: Tras 14 días de consumo se observó una reducción significativa (p&lt;0,05) del malestar físico y psicosocial. Las respuestas a los cuestionarios de percepción de efectividad mejoraron a partir del octavo día. Aumentó el acuerdo con las percepciones subjetivas de alivio del estreñimiento (81%-97%), de bienestar (90%-96%) y mejora de las sensaciones físicas (77%-97%). Al final del estudio, el 95% de los sujetos estaba satisfecho o muy satisfecho con el tratamiento elegido.  Conclusiones: El uso del producto sanitario Macrogol 4000 durante 14 días mejora el malestar físico y psicosocial al mismo tiempo que se produce un incremento de la percepción de su efectividad en individuos con estreñimiento funcional.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Introduction: Constipation has a prevalence of 14-30% in Spain, its cause is multifactorial and negatively affects people&#8217;s well-being and quality of life. Treatments for functional constipation include osmotic laxatives such as Macrogol 4000. The degree of satisfaction with laxatives is proportional to the perceived effectiveness and improvement in quality of life.  Method: a survey was conducted in Spanish pharmacies among 100 consumers who purchased Macrogol 4000 as a medical device, in order to treat the symptoms of constipation. Changes in quality of life and subjective perception of effectiveness were measured after 4, 8 and 14 days of treatment using CATI methodology, based on telephone surveys.  Results: After 14 days of consumption, a significant reduction (p&lt;0.05) in physical and psychosocial discomfort was observed. Responses on the effectiveness perception questionnaires improved after day 8. The number of responses expressing agreement with subjective perceptions of relief from constipation (81%-97%), of well-being (90%-96%) and of improved physical sensations (77%-97%) increased. At the end of the study, 95% of participants were satisfied or very satisfied with the chosen treatment.  Conclusions: The use of Macrogol 4000 for 14 days improves physical and psychosocial discomfort at the same time as there is an increase in the perception of its effectiveness in individuals with functional constipation.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[estreñimiento]]></kwd>
<kwd lng="es"><![CDATA[calidad de vida]]></kwd>
<kwd lng="es"><![CDATA[macrogol]]></kwd>
<kwd lng="es"><![CDATA[encuestas de percepción de efectividad]]></kwd>
<kwd lng="en"><![CDATA[constipation]]></kwd>
<kwd lng="en"><![CDATA[quality of life]]></kwd>
<kwd lng="en"><![CDATA[macrogol]]></kwd>
<kwd lng="en"><![CDATA[effectiveness perception surveys]]></kwd>
</kwd-group>
</article-meta>
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