<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2444-7986</journal-id>
<journal-title><![CDATA[Revista ORL]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. ORL]]></abbrev-journal-title>
<issn>2444-7986</issn>
<publisher>
<publisher-name><![CDATA[Ediciones Universidad de Salamanca]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2444-79862020000400001</article-id>
<article-id pub-id-type="doi">14201/orl.23079</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Toma de muestras nasofaríngeas para diagnóstico de COVID-19]]></article-title>
<article-title xml:lang="en"><![CDATA[Nasopharyngeal swab for the diagnosis of COVID-19]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Morales Angulo]]></surname>
<given-names><![CDATA[Carmelo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[González Zubizarreta]]></surname>
<given-names><![CDATA[Rocío]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Martin Toca]]></surname>
<given-names><![CDATA[Gema]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ramirez Bonilla]]></surname>
<given-names><![CDATA[Almudena]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gozalo Margüello]]></surname>
<given-names><![CDATA[Mónica]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodriguez Fernández]]></surname>
<given-names><![CDATA[Ana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,IDIVAL Hospital Universitario Marqués de Valdecilla Universidad de Cantabria]]></institution>
<addr-line><![CDATA[Santander ]]></addr-line>
<country>España</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2020</year>
</pub-date>
<volume>11</volume>
<numero>4</numero>
<fpage>389</fpage>
<lpage>394</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S2444-79862020000400001&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S2444-79862020000400001&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S2444-79862020000400001&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción y objetivos: La prueba de diagnóstico directo del COVID-19 de mayor sensibilidad es la toma de muestras de nasofaringe mediante un hisopo para estudio posterior mediante RT-PCR. El objetivo de nuestro trabajo es exponer pormenorizadamente la forma más adecuada de realizar dicha técnica.  Método: Descripción de los diferentes pasos necesarios para la toma de muestras nasofaríngeas en pacientes con COVID-19.  Resultados: Los pasos a tener en cuenta son: 1. Previamente se descarta que no existan contraindicaciones para la toma de muestra. 2.Etiquetado de la muestra y preparación del volante de petición. 3. Colocación de EPI según los estándares de la institución en la que se trabaja. 4. Explicación al paciente del proceso a realizar. 5. Técnica para la toma de muestra nasofaríngea 6. Retirada del EPI. 7. Manipulación y transporte de la muestra al laboratorio  Discusión y conclusiones: Dado que la sensibilidad de las muestras nasofaríngeas para diagnóstico de COVID-19 depende en gran parte de una adecuada técnica, es muy importante la formación adecuada del personal implicado en la recogida de esta. La persona formada a tal efecto debe conocer el objetivo claro de la misma, como se debe poner y quitar el EPI, conocer cómo se realiza la técnica y como se manipula la muestra.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction and objective: The diagnostic test of COVID-19 with the highest sensitivity is a nasopharyngeal sample using a swab for subsequent study using RT-PCR. The objective of our work is to explain in detail the most appropriate way to perform this technique.  Method: Description of the different steps necessary for taking a nasopharyngeal sample in patients with covid-19.  Results: The steps to take into account to get a nasopharyngeal sample in a patient with COVID-19 are: 1. Previously, it is necessary to rule out that there are no contraindications for sampling. 2. Sample labeling and preparation of the petition form. 3. Placement of PPE according to the institution rules. 4. Explanation to the patient of the process to be performed. 5. Procedure for taking a nasopharyngeal sample. 6. Withdrawal of the EPI. 7. Handling and tranportation of the sample to the laboratory.  Discussion and Conclusions: Given that the sensitivity of the nasopharyngeal simples for the diagnosis of COVID-19 depends largely on a correct technique, the adequate training of the personnel involved in this collection is very important. The examiner must know the objetive of the procedure, how top ut on and take off the PPE, know how the technique is performed and how the sample is handled.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[COVID-19]]></kwd>
<kwd lng="es"><![CDATA[SARS-CoV-2]]></kwd>
<kwd lng="es"><![CDATA[nasofaringe]]></kwd>
<kwd lng="es"><![CDATA[frotis nasofaríngeo]]></kwd>
<kwd lng="es"><![CDATA[diagnóstico]]></kwd>
<kwd lng="en"><![CDATA[COVID-19]]></kwd>
<kwd lng="en"><![CDATA[SARS-CoV-2]]></kwd>
<kwd lng="en"><![CDATA[nasopharynx]]></kwd>
<kwd lng="en"><![CDATA[nasopharyngeal swab]]></kwd>
<kwd lng="en"><![CDATA[diagnostic]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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