<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2529-850X</journal-id>
<journal-title><![CDATA[Journal of Negative and No Positive Results]]></journal-title>
<abbrev-journal-title><![CDATA[JONNPR]]></abbrev-journal-title>
<issn>2529-850X</issn>
<publisher>
<publisher-name><![CDATA[Research and Science S.L.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2529-850X2020000600616</article-id>
<article-id pub-id-type="doi">10.19230/jonnpr.3689</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Tromboembolismo Pulmonar en los pacientes con COVID-19. Angiografía con tomografía computarizada: resultados preliminares]]></article-title>
<article-title xml:lang="en"><![CDATA[Pulmonary Thromboembolism in pacients with COVID-19. Computer tomography pulmonary angiography: preliminary results]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Franco-López]]></surname>
<given-names><![CDATA[Ángeles]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="A a"/>
<xref ref-type="aff" rid="A1b"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Escribano Poveda]]></surname>
<given-names><![CDATA[Jorge]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="A a"/>
<xref ref-type="aff" rid="A2b"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Vicente Gilabert]]></surname>
<given-names><![CDATA[Nuria]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="A1a">
<institution><![CDATA[,Hospital de Vinalopó Servicio de Radiología ]]></institution>
<addr-line><![CDATA[Alicante ]]></addr-line>
<country>España</country>
</aff>
<aff id="A1b">
<institution><![CDATA[,Hospital de Torrevieja Servicio de Radiología ]]></institution>
<addr-line><![CDATA[Alicante ]]></addr-line>
<country>España</country>
</aff>
<aff id="A2a">
<institution><![CDATA[,Hospital de Vinalopó Departamento de Imagen ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>España</country>
</aff>
<aff id="A2b">
<institution><![CDATA[,Hospital de Torrevieja Departamento de Imagen ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>España</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital Comarcal de Noroeste Medicina Familiar y Comunitaria ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>España</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2020</year>
</pub-date>
<volume>5</volume>
<numero>6</numero>
<fpage>616</fpage>
<lpage>630</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S2529-850X2020000600616&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S2529-850X2020000600616&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S2529-850X2020000600616&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  Objetivo. Los pacientes con afectación pulmonar grave por COVID-19 presentan hipoxia y aumento progresivo del Dimero D por lo que los síntomas se solapan con el tromboembolismo pulmonar (TEP). La realización de AngioTC en estos pacientes es compleja y expone al personal del Servicio.En este trabajo se revisan los hallazgos clínicos, analíticos y en imagen de los pacientes con enfermedad por COVID-19 y tromboembolismo pulmonar.  Material y métodos. Se realiza un estudio retrospectivo de los pacientes ingresados en nuestros hospitales con diagnóstico de COVID-19 a los que se les realizó un angioTC para descartar o confirmar la existencia de TEP. Se analizaron parámetros clínicos y analíticos de cada uno de ellos.  Resultados. Hemos realizado 18 estudios de angioTC de arterias pulmonares a los 277 pacientes ingresados con COVID-19 entre el 15 de marzo y el 10 de abril de 2020. El diagnóstico se confirmó en todos los casos con PCR. El motivo de consulta fue hipoxemia y aumento de las cifras de DÍmero D con descenso de los otros parámetros habitualmente alterados en esta enfermedad (ferritina, LDH y proteína C). Se evidenció la existencia de TEP en 8 pacientes. En cinco casos se observó en ramas lobares y segmentarias afectando en dos casos a ramas principales y lobares; en un caso la rama trombosada era una vena pulmonar. Se observó una tendencia a la linfopenia en los pacientes con trombosis. El 50% de los pacientes estaban ingresados en la UCI. En todos los casos se observaron pequeñas adenopatías hiliares y mediastínicas  Conclusión. El TEP es una complicación de la enfermedad por COVID-19. El diagnóstico clínico es difícil de establecer por el solapamiento de la clínica y los datos analíticos de las dos entidades. Existe tendencia a la linfopenia en los pacientes con TEP.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Patients with severe pulmonary disease secondary to COVID-19 present with hipoxia and progressive increase of DDimero. For this reason these symptoms resemble pulmonary thromboembolism (TEP). AngioTC performance in these patients is complex and risky for the people involved. Clinical, analytical and image findings of patients with COVID-19 and pulmonary thromboembolism are reviewed.  Material and methods. This is a retrospective study of patients admitted in our hospitals with the diagnosis of COVID-19 in which an angioTC was practiced in order to confirm or discard TEP. Clinical and analytical parameters were analyzed.  Results. Eighteen angioTC of pulmonary arteries in admitted patients with COVID-19 between March 15 and April 10, 2020 were performed. Diagnosis was confirmed in all cases with PCR. The reason for consultation was hypoxemia and increase in DDimero with decrease in other parameters, usually altered in this disease (ferritin, LDH and protein C). TEP was confirmed in eight patients. Lobar and segmental branches were affected in five cases; in two, main and lobar arteries were involved. Pulmonary vein was thrombosed in one case. A tendency towards lymphopenia was observed in patients with thrombosis. 50% of patients were hospitalized in ICU. Small hilar and mediastinic lymph nodes were observed in all cases.  Conclusion. TEP is a complication in COVID-19 disease. Clinical diagnosis is difficult to establish due to overlapping of symptoms in both diseases. There is a tendency towards lymohopenia in patients with TEP.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[COVID-19]]></kwd>
<kwd lng="es"><![CDATA[coronavirus]]></kwd>
<kwd lng="es"><![CDATA[pandemia]]></kwd>
<kwd lng="es"><![CDATA[tromboembolismo pulmonar]]></kwd>
<kwd lng="es"><![CDATA[angioTC]]></kwd>
<kwd lng="en"><![CDATA[COVID-19]]></kwd>
<kwd lng="en"><![CDATA[coronavirus]]></kwd>
<kwd lng="en"><![CDATA[pandemic]]></kwd>
<kwd lng="en"><![CDATA[pulmonary thromboembolism]]></kwd>
<kwd lng="en"><![CDATA[angioTC]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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