<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2529-850X</journal-id>
<journal-title><![CDATA[Journal of Negative and No Positive Results]]></journal-title>
<abbrev-journal-title><![CDATA[JONNPR]]></abbrev-journal-title>
<issn>2529-850X</issn>
<publisher>
<publisher-name><![CDATA[Research and Science S.L.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2529-850X2020000900998</article-id>
<article-id pub-id-type="doi">10.19230/jonnpr.3685</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Identificación de interacciones medicamentosas potenciales en pacientes geriátricos]]></article-title>
<article-title xml:lang="en"><![CDATA[Identification of potential drug interactions in geriatric patients]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Álpizar Cortes]]></surname>
<given-names><![CDATA[José Emmanuel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Angeles Lozano]]></surname>
<given-names><![CDATA[Karina Lizeth]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ávila Ballesteros]]></surname>
<given-names><![CDATA[Daniela]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Luna Calva]]></surname>
<given-names><![CDATA[Liliana Lucila]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Torres Cano]]></surname>
<given-names><![CDATA[Wendy Dayana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Olvera Hernández]]></surname>
<given-names><![CDATA[Elena Guadalupe]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ruvalcaba Ledezma]]></surname>
<given-names><![CDATA[Jesús Carlos]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sierra Mendoza]]></surname>
<given-names><![CDATA[Rocio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Yáñez González]]></surname>
<given-names><![CDATA[Andrea]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Reynoso Vázquez]]></surname>
<given-names><![CDATA[Josefina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Autónoma del Estado de Hidalgo Instituto de Ciencias de la Salud ]]></institution>
<addr-line><![CDATA[ Hidalgo]]></addr-line>
<country>México</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Autónoma del Estado de Hidalgo Instituto de Ciencias de la Salud Área Académica de Farmacia]]></institution>
<addr-line><![CDATA[ Hidalgo]]></addr-line>
<country>México</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad Autónoma del Estado de Hidalgo Instituto de Ciencias de la Salud Área Académica de Medicina y de la Maestría en Salud Pública]]></institution>
<addr-line><![CDATA[ Hidalgo]]></addr-line>
<country>México</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Universidad Autónoma de Hidalgo Instituto de Ciencias de la Salud ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af5">
<institution><![CDATA[,Universidad Autónoma del Estado de Hidalgo Instituto de Ciencias de la Salud Área Académica de Farmacia y de la Maestría en Salud Pública]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>México</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2020</year>
</pub-date>
<volume>5</volume>
<numero>9</numero>
<fpage>998</fpage>
<lpage>1009</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S2529-850X2020000900998&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S2529-850X2020000900998&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S2529-850X2020000900998&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen Los pacientes de la tercera edad conforman el grupo etario más medicado de la sociedad, principalmente por el incremento de la prevalencia de enfermedades crónicas, por lo tanto tienen una mayor probabilidad a presentar interacciones medicamentosas debido a otros factores dependientes del estado de su organismo, presentan tres características principales que lo diferencian de otros grupos de edad: polipatología, polifarmacia y cambios fisiológicos relacionados con el envejecimiento que alteran la farmacocinética y farmacodinamia de los medicamentos.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Thepatients of the third age make up the most medicated age group in society, mainly due to the increase in the prevalence of chronic diseases, therefore they are more likely to present drug interactions due to other factors dependent on the state of their organism, they present three main characteristics that differentiate it from other age groups: polypathology, polypharmacy and physiological changes related to aging that alter the pharmacokinetics and pharmacodynamics of medications.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Interacciones medicamentosas]]></kwd>
<kwd lng="es"><![CDATA[paciente geriatrico]]></kwd>
<kwd lng="es"><![CDATA[polifarmacia]]></kwd>
<kwd lng="en"><![CDATA[Drug interactions]]></kwd>
<kwd lng="en"><![CDATA[geriatric patient]]></kwd>
<kwd lng="en"><![CDATA[polypharmacy]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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