<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2695-463X</journal-id>
<journal-title><![CDATA[Revista Española de Podología]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Esp Podol.]]></abbrev-journal-title>
<issn>2695-463X</issn>
<publisher>
<publisher-name><![CDATA[Inspira Network Group, S.L]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2695-463X2025000100013</article-id>
<article-id pub-id-type="doi">10.20986/revesppod.2025.1701/2024</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Eficacia de la toxina botulínica en la hiperhidrosis severa frente a tratamientos tópicos tradicionales. Revisión bibliográfica narrativa]]></article-title>
<article-title xml:lang="en"><![CDATA[Effectiveness of botulim toxin in severe hiperhidrosis compared to traditional topical treatments. A narrative literature review]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Vázquez González]]></surname>
<given-names><![CDATA[Javier]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Regife Fernández]]></surname>
<given-names><![CDATA[Laura]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Juárez Jiménez]]></surname>
<given-names><![CDATA[José María]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Sevilla Departamento de Podología. Facultad de Enfermería, Fisioterapia y Podología ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Spain</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2025</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2025</year>
</pub-date>
<volume>36</volume>
<numero>1</numero>
<fpage>75</fpage>
<lpage>80</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S2695-463X2025000100013&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S2695-463X2025000100013&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S2695-463X2025000100013&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen La hiperhidrosis severa es una sudoración excesiva, no relacionada con la actividad física o el aumento de la temperatura, que afecta a la población en mayor porcentaje de lo que conocemos. La alta prevalencia en etapas tempranas de la adultez condiciona la calidad de vida y la capacidad social y laboral de las personas que la padecen. Además, la amplia variedad de tratamientos existentes y la escasa, nula o inconstante respuesta de muchos de ellos dificulta la elección y favorece las complicaciones secundarias a un proceso no resuelto. De esta manera, el objetivo principal es analizar el uso de la toxina botulínica en la hiperhidrosis en general y en la localización plantar en particular, mediante una revisión bibliográfica narrativa. Se ha realizado una búsqueda en diversas bases de datos científicas durante los meses de febrero y junio de 2023. Tras aplicar criterios de inclusión y exclusión, se seleccionaron y analizaron un total de 32 artículos. De estos, 13 cumplieron con los criterios de búsqueda y se incluyeron en la discusión. Como conclusiones, se obtiene que la toxina botulínica es una técnica altamente eficaz, muy satisfactoria y posee baja tasa de complicaciones para el tratamiento de la hiperhidrosis. Sin embargo, es necesario mayor número de estudios para determinar su eficacia, dosis óptima y duración del tratamiento en zonas plantares.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Severe hyperhidrosis is excessive sweating, not related to physical activity or increased temperature, which affects a higher percentage of the population than is commonly known. Its high prevalence in early adulthood impacts the quality of life and the social and occupational capacity of those who suffer from it. Additionally, the wide variety of existing treatments and the poor, inconsistent, or absent response of many of them complicates the choice and favors secondary complications from an unresolved process. Thus, the main objective is to analyze the use of Botulinum Toxin in hyperhidrosis in general, and in plantar localization in particular, through a narrative literature review. A search was conducted in various scientific databases during the months of February and June 2023. After applying inclusion and exclusion criteria, a total of 32 articles were selected and analyzed. Of these, 13 met the search criteria and were included in the discussion. The conclusions indicate that Botulinum Toxin is a highly effective technique, very satisfactory, and has a low complication rate for the treatment of hyperhidrosis. However, a greater number of studies are needed to determine its efficacy, optimal dosage, and duration of treatment in plantar areas.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Antitranspirantes]]></kwd>
<kwd lng="es"><![CDATA[cloruro de aluminio]]></kwd>
<kwd lng="es"><![CDATA[toxina botulínica]]></kwd>
<kwd lng="es"><![CDATA[antagonistas colinérgicos]]></kwd>
<kwd lng="es"><![CDATA[hiperhidrosis]]></kwd>
<kwd lng="es"><![CDATA[iontoforesis]]></kwd>
<kwd lng="es"><![CDATA[axila]]></kwd>
<kwd lng="es"><![CDATA[bloqueantes neuromusculares]]></kwd>
<kwd lng="en"><![CDATA[Antiperspirants]]></kwd>
<kwd lng="en"><![CDATA[aluminum chloride]]></kwd>
<kwd lng="en"><![CDATA[botulinum toxin]]></kwd>
<kwd lng="en"><![CDATA[cholinergic antagonists]]></kwd>
<kwd lng="en"><![CDATA[hyperhidrosis]]></kwd>
<kwd lng="en"><![CDATA[iontophoresis]]></kwd>
<kwd lng="en"><![CDATA[axilla]]></kwd>
<kwd lng="en"><![CDATA[neuromuscular blockers]]></kwd>
</kwd-group>
</article-meta>
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