<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1139-7632</journal-id>
<journal-title><![CDATA[Pediatría Atención Primaria]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Pediatr Aten Primaria]]></abbrev-journal-title>
<issn>1139-7632</issn>
<publisher>
<publisher-name><![CDATA[Asociación Española de Pediatría de Atención Primaria]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1139-76322022000100027</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Reacción adversa a paracetamol en lactante de 2 meses: importancia de los factores coadyuvantes]]></article-title>
<article-title xml:lang="en"><![CDATA[Paracetamol toxicity in a 2-month-old infant: relevance of supporting factors]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Llorente Pelayo]]></surname>
<given-names><![CDATA[Sandra]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Orizaola Ingelmo]]></surname>
<given-names><![CDATA[Ana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Vaca Recalde]]></surname>
<given-names><![CDATA[Mª Gabriela]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Cos Cossío]]></surname>
<given-names><![CDATA[Mª Ángeles de]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gutiérrez Pascual]]></surname>
<given-names><![CDATA[Daniel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rubia Fernández]]></surname>
<given-names><![CDATA[Luis de la]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Universitario Marqués de Valdecilla Servicio de Pediatría ]]></institution>
<addr-line><![CDATA[Santander ]]></addr-line>
<country>España</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Universitario Marqués de Valdecilla Servicio de Farmacología Clínica ]]></institution>
<addr-line><![CDATA[Santander ]]></addr-line>
<country>España</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2022</year>
</pub-date>
<volume>24</volume>
<numero>93</numero>
<fpage>e135</fpage>
<lpage>e139</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_arttext&amp;pid=S1139-76322022000100027&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_abstract&amp;pid=S1139-76322022000100027&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.isciii.es/scielo.php?script=sci_pdf&amp;pid=S1139-76322022000100027&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen La intoxicación por paracetamol es la principal causa de intoxicación farmacológica en Pediatría. Aunque en el grupo de lactantes es menos frecuente, los menores de 2 meses presentan particularidades metabólicas que predisponen a la intoxicación por este fármaco. Presentamos el caso de una lactante de 2 meses con daño hepático secundario a intoxicación por paracetamol tras administración de una dosis terapéutica del mismo.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Paracetamol toxicity is the main cause of drug poisoning in children. Although less frequent in infants, those younger than 2 months, have metabolic peculiarities that predispose them to intoxication by this drug. Here we present the case of a 2-month-old infant with liver damage secondary to paracetamol intoxication when administering therapeutic doses.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Hepatotoxicidad]]></kwd>
<kwd lng="es"><![CDATA[Intoxicación]]></kwd>
<kwd lng="es"><![CDATA[Paracetamol]]></kwd>
<kwd lng="en"><![CDATA[Hepatotoxicity]]></kwd>
<kwd lng="en"><![CDATA[Paracetamol]]></kwd>
<kwd lng="en"><![CDATA[Poisoning]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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