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Archivos Españoles de Urología (Ed. impresa)

Print version ISSN 0004-0614


LLARENA IBARGUREN, Roberto et al. Neurological metastases secondary to germ cell testicular tumor. Arch. Esp. Urol. [online]. 2008, vol.61, n.8, pp.939-943. ISSN 0004-0614.

Objective: Neurological metastases secondary to urological tumors account for 12% overall. The ones derived from germ cells testicular tumors are exceptional in the age of cisplatin. Methods: We report one case of mixed germ cell tumor in a 49-year-old male patient treated with systemic chemotherapy during 18 months before presenting with severe central and peripheral neurological symptoms leading to death due to massive cerebral hemorrhage. Results: We describe three types of presentation of cerebral metastases in patients with testicular cancer. Type 1 present synchronically with the primary tumor. Type 2 are diagnosed after a period of remission after conventional cytostatic treatment. Type 3 metastases are diagnosed during the course of the disease and its treatment. Conclusions: Except unique metastases classified in groups I and 2, which are susceptible of surgery or radiosurgery, in which in response may be expected; the rest of lesions secondary to germ cell tumors have an ominous prognosis and outcomes, with short survivals.

Keywords : Germ cell tumor; Metastasis; Brain.

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